Amitriptyline Hydrochloride Prices, Trend, Chart, Demand, Market Analysis, News, Historical and Forecast Data Report 2025 Edition
Amitriptyline Hydrochloride Price Trend, Index and Forecast
Track the latest insights on amitriptyline hydrochloride price trend and forecast with detailed analysis of regional fluctuations and market dynamics across North America, Latin America, Central Europe, Western Europe, Eastern Europe, Middle East, North Africa, West Africa, Central and Southern Africa, Central Asia, Southeast Asia, South Asia, East Asia, and Oceania.
Amitriptyline Hydrochloride Prices Outlook Q3 2025
- USA: USD 46,544/MT
- Germany: USD 37,320/MT
- India: USD 35,615/MT
- Brazil: USD 58,128/MT
- China: USD 34,835/MT
Amitriptyline Hydrochloride Price Chart
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During the third quarter of 2025, the amitriptyline hydrochloride prices in the USA reached 46,544 USD/MT in September. Prices strengthened slightly relative to the second quarter as demand from the antidepressant formulation segment remained firm. Supply became tighter as procurement of key intermediates experienced intermittent delays. Steady prescription demand and measured domestic output contributed to a firmer pricing environment.
During the third quarter of 2025, the amitriptyline hydrochloride prices in Germany reached 37,320 USD/MT in September. Prices increased compared with the prior quarter, driven by consistent offtake from pharmaceutical manufacturers and higher quality-assurance compliance costs. Import flows were somewhat constrained by lengthened transit times from Asia, tightening supply buffers and keeping distributors active in replenishment cycles.
During the third quarter of 2025, the amitriptyline hydrochloride prices in India reached 35,615 USD/MT in September. Prices showed a mild upward shift versus the previous quarter due to continued growth in domestic formulation demand and limited fluctuations in active ingredient availability. Export commitments to Europe and Africa remained steady, reducing excess supply and supporting a firmer market tone.
During the third quarter of 2025, the amitriptyline hydrochloride prices in Brazil reached 58,128 USD/MT in September. Prices moved higher relative to the second quarter, supported by rising procurement needs from generics manufacturers and higher landed costs for imported material. Slower port throughput and currency-driven cost fluctuations also shaped market sentiment, sustaining upward pricing direction across the period.
During the third quarter of 2025, the amitriptyline hydrochloride prices in China reached 34,835 USD/MT in September. Prices increased slightly from the previous quarter as producers adjusted operating rates due to moderated availability of chemical intermediates. Domestic offtake from formulators remained consistent, while export inquiries stayed firm, reducing spot availability and reinforcing the price increase.
Amitriptyline Hydrochloride Prices Outlook Q2 2025
- USA: USD 46,243/MT
- Germany: USD 36,994/MT
- India: USD 35,572/MT
- Brazil: USD 57,804/MT
- China: USD 34,762/MT
During the second quarter of 2025, the amitriptyline hydrochloride prices in the USA reached 46,243 USD/MT in June. Prices advanced as demand from core pharmaceutical customers strengthened. Supply chains operated smoothly, although rising production costs and increased import checking standards added modest pressure. Manufacturers maintained measured inventory positions to balance procurement cycles.
During the second quarter of 2025, the amitriptyline hydrochloride prices in Germany reached 36,994 USD/MT in June. Prices improved as stable offtake continued across the antidepressant and CNS drug segments. Importers faced slightly higher logistics-related expenses and longer documentation processing. These factors encouraged earlier ordering, supporting firmer sentiment throughout the quarter.
During the second quarter of 2025, the amitriptyline hydrochloride prices in India reached 35,572 USD/MT in June. Prices moved upward in response to consistent domestic formulation demand and strong movement toward export markets. Supply remained balanced, though certain manufacturers experienced longer lead times for raw materials. Steady utilization rates across facilities maintained upward pressure on price levels.
During the second quarter of 2025, the amitriptyline hydrochloride prices in Brazil reached 57,804 USD/MT in June. Prices advanced as import-dependent buyers navigated fluctuations in procurement costs tied to currency and freight variations. Demand from local producers of psychiatric medicines remained healthy. Regional logistics constraints at major ports also contributed to firmer pricing.
During the second quarter of 2025, the amitriptyline hydrochloride prices in China reached 34,762 USD/MT in June. Prices reflected moderate firmness as manufacturers balanced operating rates and export obligations. Domestic formulation demand remained steady, while procurement delays for upstream intermediates created slight constraints. These influences supported the upward movement through the quarter.
Regional Coverage
The report provides a detailed analysis of the market across different regions, each with unique pricing dynamics influenced by localized market conditions, supply chain intricacies, and geopolitical factors. This includes price trends, price forecast and supply and demand trends for each region, along with spot prices by major ports. The report also provides coverage of FOB and CIF prices, as well as the key factors influencing the amitriptyline hydrochloride prices.
Europe Amitriptyline Hydrochloride Price Trend
Q3 2025:
As per the amitriptyline hydrochloride price index, Europe experienced firm pricing conditions as demand from psychiatric drug manufacturers remained dependable across Western, Northern, and Central Europe. Import flows from Asia were impacted by lengthened maritime transit schedules, causing slower‐than-usual restocking cycles among German, Dutch, and Scandinavian distributors. Several European production hubs also faced rising workforce and facility-compliance costs, which intensified pressure on operating margins. Inland transport networks, including key north–south chemical corridors, saw periodic congestion that further constrained distribution flexibility and reinforced consistent procurement activity from formulation plants.
Q2 2025:
Europe recorded steady price improvement with continued interest from CNS drug formulation clusters in Germany, France, Italy, and Poland. Importers faced variations in landed costs as currency movements shifted sourcing economics for shipments arriving through major ports such as Rotterdam and Antwerp. Manufacturers maintained reliable purchasing patterns, encouraged by stable clinical and commercial production cycles. Intermittent documentation and regulatory checks extended clearance times at certain customs points, prompting more risk-averse inventory planning across the region and supporting a disciplined procurement rhythm.
This analysis can be extended to include detailed amitriptyline hydrochloride price information for a comprehensive list of countries.
| Region | Countries Covered |
|---|---|
| Europe | Germany, France, United Kingdom, Italy, Spain, Russia, Turkey, Netherlands, Poland, Sweden, Belgium, Austria, Ireland, Switzerland, Norway, Denmark, Romania, Finland, Czech Republic, Portugal, and Greece, among other European countries. |
North America Amitriptyline Hydrochloride Price Trend
Q3 2025:
As per the amitriptyline hydrochloride price index, North American pricing remained firm, supported by predictable demand from antidepressant manufacturers and strong distribution activity in both the United States and Canada. Delivery schedules were affected as coastal import gateways encountered slower container movement, influencing inventory distribution across inland pharmaceutical hubs. Higher facility operating costs, particularly in synthetic-chemical manufacturing corridors, contributed to a more cautious supply posture. Stable prescription volumes and coordinated sourcing strategies among major drugmakers helped maintain well-managed inventory cycles across the region.
Q2 2025:
North America recorded a stable pricing environment with consistent offtake from generics producers and solid manufacturing activity concentrated in key states such as New Jersey, North Carolina, and California. Import arrivals were more regular compared with earlier quarters, enabling smoother planning for distributors. Transportation networks across the Midwest and East Coast functioned with fewer interruptions, supporting orderly delivery of active pharmaceutical ingredients. Producers and contract manufacturers maintained moderated output to align with predictable purchasing behavior, contributing to balanced supply conditions across the market.
Specific amitriptyline hydrochloride historical data within the United States and Canada can also be provided.
| Region | Countries Covered |
|---|---|
| North America | United States and Canada |
Middle East and Africa Amitriptyline Hydrochloride Price Trend
Q3 2025:
As per amitriptyline hydrochloride price chart, the prices in the Middle East and Africa fluctuated due to a complex interplay of factors, primarily driven by supply chain disruptions, seasonal demand shifts, and geopolitical influences.
Q2 2025:
The report explores the amitriptyline hydrochloride pricing trends and amitriptyline hydrochloride price chart in the Middle East and Africa, considering factors like regional industrial growth, the availability of natural resources, and geopolitical tensions that uniquely influence market prices.
In addition to region-wise data, information on amitriptyline hydrochloride prices for countries can also be provided.
| Region | Countries Covered |
|---|---|
| Middle East & Africa | Saudi Arabia, UAE, Israel, Iran, South Africa, Nigeria, Oman, Kuwait, Qatar, Iraq, Egypt, Algeria, and Morocco, among other Middle Eastern and African countries. |
Asia Pacific Amitriptyline Hydrochloride Price Trend
Q3 2025:
Asia Pacific recorded firm pricing as demand from antidepressant and CNS drug manufacturers remained strong in China, India, South Korea, and Southeast Asia. Production adjustments at Chinese facilities, influenced by moderated availability of key intermediates, reduced surplus quantities typically earmarked for export. Import-reliant markets such as Indonesia, Thailand, and the Philippines faced additional expense variability tied to freight market fluctuations and domestic currency pressures. Inland logistics congestion in major commercial centers, compounded by tight trucking capacity during peak distribution periods, contributed to uneven availability across the region.
Q2 2025:
The region showed stable to mildly firm sentiment as buying from pharmaceutical formulation industries remained consistent. China’s moderated output levels influenced export distribution patterns, affecting supply across neighboring Asian markets. India saw steady procurement tied to both domestic consumption and continued export programs. Southeast Asian buyers adjusted purchasing schedules in response to evolving freight conditions and shifting raw-material intake at Chinese production clusters. These factors contributed to orderly yet dynamic sourcing activity across the broader Asia Pacific market.
This amitriptyline hydrochloride price analysis can be expanded to include a comprehensive list of countries within the region.
| Region | Countries Covered |
|---|---|
| Asia Pacific | China, India, Indonesia, Pakistan, Bangladesh, Japan, Philippines, Vietnam, Thailand, South Korea, Malaysia, Nepal, Taiwan, Sri Lanka, Hongkong, Singapore, Australia, and New Zealand, among other Asian countries. |
Latin America Amitriptyline Hydrochloride Price Trend
Q3 2025:
Latin America experienced upward pricing momentum driven by consistent demand from psychiatric medicine manufacturers in Brazil, Argentina, Chile, and Colombia. Heavy import dependence left buyers vulnerable to fluctuations in freight charges and currency shifts, especially in economies facing periodic volatility. Inland logistics inefficiencies, including longer movement times from key Atlantic ports toward interior pharmaceutical clusters, raised operational burdens. Regional manufacturers continued to report firm consumption trends, encouraging steady purchasing behavior despite ongoing supply chain complexities.
Q2 2025:
Latin American prices advanced moderately as the market navigated variable procurement expenses linked to currency and shipping dynamics. Import arrivals were irregular, prompting manufacturers to adopt pragmatic stocking strategies to avoid supply disruptions. Demand from antidepressant drug producers remained stable across major markets, providing a consistent baseline for purchasing. Variability in inland freight efficiency and administrative processes at customs checkpoints contributed to uneven restocking, shaping the controlled yet upward-tilted sentiment noted during the period.
This comprehensive review can be extended to include specific countries within the region.
| Region | Countries Covered |
|---|---|
| Latin America | Brazil, Mexico, Argentina, Columbia, Chile, Ecuador, and Peru, among other Latin American countries. |
Amitriptyline Hydrochloride Pricing Report, Market Analysis, and News
IMARC's latest publication, “Amitriptyline Hydrochloride Prices, Trend, Chart, Demand, Market Analysis, News, Historical and Forecast Data Report 2025 Edition,” presents a detailed examination of the amitriptyline hydrochloride market, providing insights into both global and regional trends that are shaping prices. This report delves into the spot price of amitriptyline hydrochloride at major ports and analyzes the composition of prices, including FOB and CIF terms. It also presents detailed amitriptyline hydrochloride prices trend analysis by region, covering North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. The factors affecting amitriptyline hydrochloride pricing, such as the dynamics of supply and demand, geopolitical influences, and sector-specific developments, are thoroughly explored. This comprehensive report helps stakeholders stay informed with the latest market news, regulatory updates, and technological progress, facilitating informed strategic decision-making and forecasting.
Amitriptyline Hydrochloride Industry Analysis
The global amitriptyline hydrochloride industry size reached USD 623.88 Million in 2025. By 2034, IMARC Group expects the market to reach USD 825.39 Million, at a projected CAGR of 3.16% during 2026-2034. Growing demand for antidepressant medications, rising prevalence of neurological and mental health disorders, and expanding generic drug manufacturing are driving the global amitriptyline hydrochloride market, supported by broader access to pharmaceutical treatments worldwide.
Latest News and Developments:
- June 2025: JB Chemicals & Pharmaceuticals received USFDA approval for its generic amitriptyline hydrochloride tablets, enabling the company to market the antidepressant in the United States. The approval strengthened its position in regulated markets by expanding its CNS portfolio and opening a new revenue stream from US generics.
Product Description
Amitriptyline hydrochloride is a tricyclic antidepressant (TCA) used primarily in the treatment of major depressive disorder. It functions chemically as amitriptyline hydrochloride salt, affecting the brain's neurotransmitter balance, especially that of serotonin and norepinephrine.
Besides its primary use in treating depression, amitriptyline hydrochloride is employed in a variety of clinical settings due to its diverse pharmacological effects. It is frequently prescribed for chronic pain management, including neuropathic pain, fibromyalgia, and migraine prevention. Additionally, this medication can be effective in managing symptoms of anxiety disorders, and it is sometimes used off-label for insomnia due to its soothing properties.
Amitriptyline hydrochloride is characterized by its long half-life, allowing for once-daily dosing, which enhances patient compliance. Additionally, its broad-spectrum activity in affecting multiple neurotransmitter systems provides antidepressant effects and contributes to its analgesic and anxiolytic properties.
Report Coverage
| Key Attributes | Details |
|---|---|
| Product Name | Amitriptyline Hydrochloride |
| Report Features | Exploration of Historical Trends and Market Outlook, Industry Demand, Industry Supply, Gap Analysis, Challenges, Amitriptyline Hydrochloride Price Analysis, and Segment-Wise Assessment. |
| Currency/Units | US$ (Data can also be provided in local currency) or Metric Tons |
| Region/Countries Covered | The current coverage includes analysis at the global and regional levels only. Based on your requirements, we can also customize the report and provide specific information for the following countries: Asia Pacific: China, India, Indonesia, Pakistan, Bangladesh, Japan, Philippines, Vietnam, Thailand, South Korea, Malaysia, Nepal, Taiwan, Sri Lanka, Hongkong, Singapore, Australia, and New Zealand* Europe: Germany, France, United Kingdom, Italy, Spain, Russia, Turkey, Netherlands, Poland, Sweden, Belgium, Austria, Ireland, Switzerland, Norway, Denmark, Romania, Finland, Czech Republic, Portugal and Greece* North America: United States and Canada Latin America: Brazil, Mexico, Argentina, Columbia, Chile, Ecuador, and Peru* Middle East & Africa: Saudi Arabia, UAE, Israel, Iran, South Africa, Nigeria, Oman, Kuwait, Qatar, Iraq, Egypt, Algeria, and Morocco* *The list of countries presented is not exhaustive. Information on additional countries can be provided if required by the client. |
| Information Covered for Key Suppliers |
|
| Customization Scope | The report can be customized as per the requirements of the customer |
| Report Price and Purchase Option |
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| Delivery Format | PDF and Excel through email (We can also provide the editable version of the report in PPT/Word format on special request) |
Key Benefits for Stakeholders:
- IMARC’s report presents a detailed analysis of amitriptyline hydrochloride pricing, covering global and regional trends, spot prices at key ports, and a breakdown of Ex Works, FOB, and CIF prices.
- The study examines factors affecting amitriptyline hydrochloride price trend, including raw material costs, supply-demand shifts, geopolitical impacts, and industry developments, offering insights for informed decision-making.
- The competitive landscape review equips stakeholders with crucial insights into the latest market news, regulatory changes, and technological advancements, ensuring a well-rounded, strategic overview for forecasting and planning.
- IMARC offers various subscription options, including monthly, quarterly, and biannual updates, allowing clients to stay informed with the latest market trends, ongoing developments, and comprehensive market insights. The amitriptyline hydrochloride price charts ensure our clients remain at the forefront of the industry.
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