Bispecific Antibodies Market Report by Indication (Cancer, Inflammatory and Autoimmune Disorder, and Others), and Region 2024-2032

Bispecific Antibodies Market Report by Indication (Cancer, Inflammatory and Autoimmune Disorder, and Others), and Region 2024-2032

Report Format: PDF+Excel | Report ID: SR112024A8396
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Market Overview:

The global bispecific antibodies market size reached US$ 580.5 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 1,064.2 Million by 2032, exhibiting a growth rate (CAGR) of 6.97% during 2024-2032. The growing product utilization to treat infectious diseases, increase product adoption in the treatment of autoimmune disorders, extensive research and development (R&D) activities, and the implementation of favorable regulatory policies are some of the major factors propelling the market.

Report Attribute
Key Statistics
Base Year
Forecast Years
Historical Years
Market Size in 2023 US$ 580.5 Million
Market Forecast in 2032 US$ 1,064.2 Million
Market Growth Rate (2024-2032) 6.97%

Bispecific antibodies refer to engineered proteins that possess dual antigen specificity, capable of recognizing and binding two different target molecules simultaneously. They are manufactured using advanced recombinant deoxyribonucleic acid (DNA) technology, allowing for precise manipulation of their structural and functional properties. Bispecific antibodies are widely used in oncology, immunology, and infectious diseases. They offer increased tumor selectivity, reduced off-target effects, and improved drug delivery to specific cell types. Bispecific antibodies also enhance the efficacy of current treatments and address certain forms of drug resistance, making them suitable for personalized therapies.

Bispecific Antibodies Market

The escalating prevalence of chronic diseases is facilitating product demand as it allows the simultaneous targeting of multiple disease-specific antigens, thus enhancing the efficacy of treatment options. Furthermore, the implementation of favorable regulatory policies by several governments to facilitate the development and commercialization of bispecific antibodies and encourage their adoption in clinical practice is contributing to the market growth. Additionally, the growing collaborations between industry players, academic institutions, and research organizations, fostering the development of novel bispecific antibody drugs, are acting as another growth-inducing factor. Along with this, the presence of a robust pipeline of bispecific antibody candidates that are in various stages of development is providing an impetus to the market growth. Other factors, including rapid expansion of the healthcare infrastructure, increasing investment in the development of advanced production methods, and the growing demand for precision medicine, are anticipated to drive the market growth.

Bispecific Antibodies Market Trends/Drivers:

The growing product utilization to treat infectious diseases.

Bispecific antibodies are designed to bind with viral surface proteins and simultaneously engage immune cells, thus facilitating viral neutralization and clearance. They also target bacterial pathogens by binding to specific bacterial antigens and engaging immune cells or antimicrobial mechanisms. Furthermore, bispecific antibodies offer a potential approach to combat fungal infections by targeting fungal antigens and recruiting immune cells for clearance. In line with this, they enhance the activity of immune effector cells, such as macrophages, natural killer (NK) cells, and neutrophils, to eliminate fungal pathogens. Moreover, bispecific antibodies can mediate the clearance of parasites through immune mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) or by inhibiting parasite invasion or replication. Apart from this, they can be engineered to simultaneously target resistant pathogens to overcome antimicrobial resistance.

The increasing product adoption in the treatment of autoimmune disorder

Bispecific antibodies simultaneously bind to immune cells and molecules involved in immune activation pathways. By engaging immune cells such as T cells or B cells, bispecific antibodies can modulate their activation, proliferation, and differentiation, thus regulating the immune response in autoimmune disorders. They also target specific cytokines or chemokines that drive inflammatory responses in autoimmune disorders, which aids in dampening the inflammatory cascade and reducing tissue damage. Furthermore, bispecific antibodies can promote immune tolerance by engaging regulatory immune cells or inducing tolerogenic signals, which aids in restoring immune homeostasis and preventing autoreactive immune responses in autoimmune disorders. Moreover, they simultaneously block two immune checkpoint molecules that regulate immune cell activity, which aids in overcoming immune exhaustion and promoting immune responses against self-antigens.

Extensive research and development (R&D) activities

The recent advancements in genetic engineering techniques, such as gene knockouts and knock-ins, which aids in modifying cell lines, optimizing protein expression, and enhancing the productivity and stability of bispecific antibodies, are contributing to the market growth. Furthermore, the introduction of novel expression systems, which allow researchers to choose the most suitable expression for specific bispecific antibody production needs, is positively influencing the market growth. Additionally, the integration of advanced process monitoring and control systems, which enable real-time adjustments and optimization of the manufacturing process, resulting in improved yields and consistency, is strengthening the market growth. Moreover, the utilization of advanced purification techniques, such as affinity, ion exchange, and size exclusion chromatography, which allow efficient separation of the desired products, is favoring the market growth.

Bispecific Antibodies Industry Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the global bispecific antibodies market report, along with forecasts at the global, regional, and country levels from 2024-2032. Our report has categorized the market based on the indication.

Breakup by Indication:

  • Cancer
  • Inflammatory and Autoimmune Disorder
  • Others

Cancer holds the largest market share.

The report has provided a detailed breakup and analysis of the market based on the indication. This includes cancer, inflammatory and autoimmune disorder, and others. According to the report, cancer represented the largest market segment.

Bispecific antibodies are widely used in cancer treatment to redirect the patient's own T cells to specifically recognize and kill cancer cells. They are designed to bring T cells in close proximity to cancer cells, leading to the formation of an immunological synapse and the activation of T cell-mediated cytotoxicity. Furthermore, bispecific antibodies enable simultaneous targeting of multiple antigens expressed on cancer cells, leading to enhanced tumor specificity and efficacy. Additionally, they are engineered to bind to a cancer-specific antigen and a receptor involved in tumor growth and survival signaling pathways, which hinder their growth and promote apoptosis. Moreover, bispecific antibodies deliver cytotoxic payloads directly to cancer cells, thus minimizing systemic toxicity and improving therapeutic efficacy. Apart from this, they can also be combined with conventional chemotherapy, radiotherapy, and targeted therapies, to improve treatment outcomes.

Breakup by Region:

  • North America
    • United States
    • Canada
  • Europe
    • Germany
    • France
    • United Kingdom
    • Italy
    • Spain
    • Others
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Indonesia
    • Others
  • Latin America
    • Brazil
    • Mexico
    • Others
  • Middle East and Africa

North America exhibits a clear dominance in the market, accounting for the largest bispecific antibodies market share.

The report has also provided a comprehensive analysis of all the major regional markets, which includes North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represented the largest market segment.

North America has a strong and mature biopharmaceutical industry comprising research institutions, biotechnology companies, and pharmaceutical giants that are actively engaged in the development and commercialization of innovative biologics such as bispecific antibodies. Furthermore, the region is at the forefront of technological advancements and possesses significant research capabilities in the field of biopharmaceuticals, which is contributing to the market growth. Additionally, the implementation of supportive policies by regional governments to streamline regulatory processes and facilitate faster market access for innovative therapies is strengthening the market growth. Moreover, the presence of a favorable investment climate, venture capital support, and government initiatives that enable companies to advance their clinical programs, conduct robust clinical trials, and accelerate market entry is favoring the market growth.

Competitive Landscape:

The top companies in the market are expanding their product portfolio by developing a diverse range of bispecific antibodies targeting different diseases and therapeutic areas. They are investing in research and development (R&D) to identify novel targets, optimize antibody designs, and advance candidates through preclinical and clinical stages. Furthermore, several key players are engaged in strategic partnerships with other biopharmaceutical companies, academic institutions, and research organizations to access complementary technologies, leverage expertise, share resources, and jointly develop and commercialize bispecific antibodies. Moreover, leading companies are aiming to expand their market presence by establishing subsidiaries, forming alliances with local partners, and engaging in licensing agreements. Apart from this, aggressive branding and marketing activities by manufacturers to increase product visibility and generate demand is acting as another growth-inducing factor.

The report has provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the key players in the market include:

  • Abbvie Inc.
  • Adimab LLC
  • Affimed GmbH
  • Akeso Inc.
  • Amgen Inc.
  • Astrazeneca Plc
  • Immunocore Limited
  • Macrogenics Inc.
  • Merus N.V.
  • Regeneron Pharmaceuticals Inc.
  • Roche Holding AG

Bispecific Antibodies Market Report Scope:

Report Features Details
Base Year of the Analysis 2023
Historical Period 2018-2023
Forecast Period 2024-2032
Units US$ Million
Scope of the Report Exploration of Historical and Forecast Trends, Industry Catalysts and Challenges, Segment-Wise Historical and Predictive Market Assessment: 
  • Indication
  • Region 
Indications Covered Cancer, Inflammatory and Autoimmune Disorder, Others
Regions Covered Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered United States, Canada, Germany, France, United Kingdom, Italy, Spain, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered Abbvie Inc., Adimab LLC, Affimed GmbH, Akeso Inc., Amgen Inc., Astrazeneca Plc, Immunocore Limited, Macrogenics Inc., Merus N.V., Regeneron Pharmaceuticals Inc., Roche Holding AG, etc.
Customization Scope 10% Free Customization
Report Price and Purchase Option Single User License: US$ 3899
Five User License: US$ 4899
Corporate License: US$ 5899
Post-Sale Analyst Support 10-12 Weeks
Delivery Format PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request)

Key Questions Answered in This Report:

  • How has the global bispecific antibodies market performed so far, and how will it perform in the coming years?
  • What are the drivers, restraints, and opportunities in the global bispecific antibodies market?
  • What is the impact of each driver, restraint, and opportunity on the global bispecific antibodies market?
  • What are the key regional markets?
  • Which countries represent the most attractive bispecific antibodies market?
  • What is the breakup of the market based on the indication?
  • Which is the most attractive indication in the bispecific antibodies market?
  • What is the competitive structure of the global bispecific antibodies market?
  • Who are the key players/companies in the global bispecific antibodies market?

Key Benefits for Stakeholders:

  • IMARC’s report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the bispecific antibodies market from 2018-2032.
  • The research study provides the latest information on the market drivers, challenges, and opportunities in the global bispecific antibodies market.
  • The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
  • Porter's five forces analysis assist stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the bispecific antibodies industry and its attractiveness.
  • Competitive landscape allows stakeholders to understand their competitive environment and provides an insight into the current positions of key players in the market.

Need more help?

  • Speak to our experienced analysts for insights on the current market scenarios.
  • Include additional segments and countries to customize the report as per your requirement.
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Bispecific Antibodies Market Report by Indication (Cancer, Inflammatory and Autoimmune Disorder, and Others), and Region 2024-2032
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