Global Gene Therapy Market to Reach USD 17.9 Billion by 2033, Propelled by Rising Prevalence of Genetic and Acquired Diseases

November 12, 2024 | Healthcare

The latest report by IMARC Group, titled "Gene Therapy Market Report by Gene Type (Antigen, Cytokine, Tumor Suppressor, Suicide Gene, Deficiency, Growth Factors, Receptors, and Others), Vector Type (Viral Vector, Non-Viral Techniques), Delivery Method (In-Vivo Gene Therapy, Ex-Vivo Gene Therapy), Application (Oncological Disorders, Rare Diseases, Cardiovascular Diseases, Neurological Disorders, Infectious Disease, and Others), and Region 2025-2033," finds that the global gene therapy market size reached USD 5.8 Billion in 2024. Gene therapy refers to an advanced medical technique that involves modifying the genes inside the cells of the patient's body to treat or prevent the progression of the disease. It works by replacing a defective gene with a new, normal and healthy gene in a cell to cure the disease or improve the body's ability to fight it. It is also used to treat numerous chronic and genetic disorders in human beings that have no other cures. Nowadays, manufacturers are offering a wide variety of gene therapy products, including plasmid deoxyribonucleic acid (DNA), human gene-editing technology, patient-derived cellular gene therapy, viral vectors, and bacterial vectors, which is currently escalating their demand across the globe.

Global Gene Therapy Market Trends:

The rising prevalence of genetic and acquired diseases, such as cancer, diabetes, cardiovascular diseases (CVDs), cystic fibrosis, and acquired immunodeficiency syndrome (AIDS), represents the primary factor driving the market growth. Besides this, the expanding geriatric population that is more susceptible to developing such chronic health conditions has catalyzed the product demand. Additionally, there has been a significant increase in government support and funding for gene therapy research. Along with this, the growing awareness regarding the benefits of gene therapy and easy accessibility to healthcare facilities have accelerated the product adoption rate. Furthermore, several key players are engaging in research and development (R&D) activities and making heavy investments toward product innovations to gain a competitive edge. Moreover, the introduction of new gene therapy that provides a safer and non-addictive alternative to opioids in treating various chronic pain conditions, such as lower back pain and rare neuropathic pain disorders, has propelled the market growth. Other factors, including the increasing approvals of gene therapy products, favorable reimbursement policies, improving healthcare infrastructure, rising consumer healthcare expenditure, and technological advancements, are also providing a positive impact on the market growth. Looking forward, IMARC Group expects the market to reach USD 17.9 Billion by 2033, growing at a CAGR of 13.3% during 2025-2033.

Market Summary:

Based on the gene type, the market has been segregated into antigen, cytokine, tumor suppressor, suicide gene, deficiency, growth factors, receptors, and others.
The market has been divided based on the vector type into viral vector (adenoviruses, lentiviruses, retroviruses, adeno-associated virus, herpes simplex virus, poxvirus, vaccinia virus, and others) and non-viral techniques (naked and plasmid vectors, gene gun, electroporation, lipofection, and others).
Based on the delivery method, the market has been bifurcated into in-vivo and ex-vivo gene therapy.
On the basis of the application, the market has been classified into oncological disorders, rare diseases, cardiovascular diseases, neurological disorders, infectious disease, and others.
Region-wise, the market has been segmented into North America (the United States and Canada), Asia-Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others), Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others), Latin America (Brazil, Mexico, and others), and Middle East and Africa.
The competitive landscape of the market has also been analyzed, with some of the key players being Abeona Therapeutics Inc., Adaptimmune Therapeutics plc, Adverum Biotechnologies Inc., Amgen Inc., Astellas Pharma Inc., Biogen Inc., Bluebird Bio Inc., Mustang Bio Inc. (Fortress Biotech Inc.), Novartis International AG, Orchard Therapeutics plc, UniQure N.V., and Voyager Therapeutics Inc.

Report Coverage:

Report Features	Details
Base Year of the Analysis	2024
Historical Period	2019-2024
Forecast Period	2025-2033
Units	Billion USD
Segment Coverage	Gene Type, Vector Type, Delivery Method, Application, Region
Region Covered	Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered	United States, Canada, Germany, France, United Kingdom, Italy, Spain, Russia, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered	Abeona Therapeutics Inc., Adaptimmune Therapeutics plc, Adverum Biotechnologies Inc., Amgen Inc., Astellas Pharma Inc., Biogen Inc., Bluebird Bio Inc., Mustang Bio Inc. (Fortress Biotech Inc.), Novartis AG, Orchard Therapeutics plc, UniQure N.V. and Voyager Therapeutics Inc.
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Global Gene Therapy Market to Reach USD 17.9 Billion by 2033, Propelled by Rising Prevalence of Genetic and Acquired Diseases

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