Market Overview:
The 7 major hereditary central nervous system demyelinating diseases markets are expected to exhibit a CAGR of 9.65% during 2024-2034.
Report Attribute
|
Key Statistics
|
Base Year
|
2023
|
Forecast Years
|
2024-2034
|
Historical Years
|
2018-2023
|
Market Growth Rate 2024-2034 |
9.65% |
The hereditary central nervous system demyelinating diseases market has been comprehensively analyzed in IMARC's new report titled "Hereditary Central Nervous System Demyelinating Diseases Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hereditary central nervous system demyelinating diseases (HCNSDD) comprise a group of rare inherited disorders characterized by the progressive loss of myelin, the protective sheath that covers nerve fibers in the central nervous system (CNS). Myelin facilitates efficient nerve signal transmission, and its deterioration results in a range of neurological symptoms. Common indications of HCNSDD encompass a variety of motor and sensory impairments, including muscle weakness, poor coordination, tremors, and difficulty walking. In some cases, cognitive and visual disturbances, as well as speech and swallowing difficulties, may also manifest. Since these diseases have a genetic basis, patients may present with symptoms at different ages, with severity varying from mild to debilitating. Diagnosing HCNSDD involves a combination of clinical evaluation, neuroimaging techniques like magnetic resonance imaging (MRI), and genetic testing. MRI scans often reveal characteristic patterns of demyelination and atrophy within the CNS. Genetic testing identifies mutations in specific genes associated with these disorders, aiding in accurate diagnosis and classification.
The escalating cases of mutations in specific genes, which can affect proteins involved in myelin production, maintenance, or the regulation of the immune response, are primarily driving the hereditary central nervous system demyelinating diseases market. In addition to this, the inflating utilization of targeted pharmaceutical treatments, including enzyme replacement therapies and immunomodulatory agents, that aim to alleviate symptoms and decelerate the progression of the ailment in patients is also creating a positive outlook for the market. Moreover, the widespread adoption of advanced diagnostic modalities like next-generation sequencing for enhancing the early detection and understanding of these disorders is further bolstering the market growth. Apart from this, the rising usage of rehabilitative measures, such as physical therapy and occupational therapy, is acting as another significant growth-inducing factor. These therapies are crucial in maintaining functional independence and improving the quality of life by focusing on mobility, fine motor skills, and adaptive strategies. Additionally, the increasing research initiatives surrounding gene therapy, since it can help to replace or repair the defective genes that cause the loss of myelin in individuals suffering from HCNSDD, are expected to drive the hereditary central nervous system demyelinating diseases market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the hereditary central nervous system demyelinating diseases market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hereditary central nervous system demyelinating diseases and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hereditary central nervous system demyelinating diseases market in any manner.
Time Period of the Study
- Base Year: 2023
- Historical Period: 2018-2023
- Market Forecast: 2024-2034
Countries Covered
- United States
- Germany
- France
- United Kingdom
- Italy
- Spain
- Japan
Analysis Covered Across Each Country
- Historical, current, and future epidemiology scenario
- Historical, current, and future performance of the hereditary central nervous system demyelinating diseases market
- Historical, current, and future performance of various therapeutic categories in the market
- Sales of various drugs across the hereditary central nervous system demyelinating diseases market
- Reimbursement scenario in the market
- In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current hereditary central nervous system demyelinating diseases marketed drugs and late-stage pipeline drugs.
In-Market Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Drugs |
Company Name |
Libmeldy (Atidarsagene autotemcel) |
Orchard Therapeutics |
FBX-101 |
Forge Biologics |
AAV9 BBP-812 |
Aspa Therapeutics |
rAAV-Olig001-ASPA |
Myrtelle |
ION373 |
Ionis Pharmaceuticals |
Leriglitazone |
Minoryx Therapeutics |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Key Questions Answered in this Report:
Market Insights
- How has the hereditary central nervous system demyelinating diseases market performed so far and how will it perform in the coming years?
- What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
- What was the country-wise size of the hereditary central nervous system demyelinating diseases market across the seven major markets in 2023 and what will it look like in 2034?
- What is the growth rate of the hereditary central nervous system demyelinating diseases market across the seven major markets and what will be the expected growth over the next ten years?
- What are the key unmet needs in the market?
Epidemiology Insights
- What is the number of prevalent cases (2018-2034) of hereditary central nervous system demyelinating diseases across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hereditary central nervous system demyelinating diseases by age across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hereditary central nervous system demyelinating diseases by gender across the seven major markets?
- What is the number of prevalent cases (2018-2034) of hereditary central nervous system demyelinating diseases by type across the seven major markets?
- How many patients are diagnosed (2018-2034) with hereditary central nervous system demyelinating diseases across the seven major markets?
- What is the size of the hereditary central nervous system demyelinating diseases patient pool (2018-2023) across the seven major markets?
- What would be the forecasted patient pool (2024-2034) across the seven major markets?
- What are the key factors driving the epidemiological trend of hereditary central nervous system demyelinating diseases?
- What will be the growth rate of patients across the seven major markets?
Hereditary Central Nervous System Demyelinating Diseases: Current Treatment Scenario, Marketed Drugs and Emerging Therapies
- What are the current marketed drugs and what are their market performance?
- What are the key pipeline drugs and how are they expected to perform in the coming years?
- How safe are the current marketed drugs and what are their efficacies?
- How safe are the late-stage pipeline drugs and what are their efficacies?
- What are the current treatment guidelines for hereditary central nervous system demyelinating diseases drugs across the seven major markets?
- Who are the key companies in the market and what are their market shares?
- What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the hereditary central nervous system demyelinating diseases market?
- What are the key regulatory events related to the hereditary central nervous system demyelinating diseases market?
- What is the structure of clinical trial landscape by status related to the hereditary central nervous system demyelinating diseases market?
- What is the structure of clinical trial landscape by phase related to the hereditary central nervous system demyelinating diseases market?
- What is the structure of clinical trial landscape by route of administration related to the hereditary central nervous system demyelinating diseases market?