The 7 major alkaptonuria markets reached a value of USD 11.9 Million in 2024. Looking forward, IMARC Group expects the 7MM to reach USD 26.5 Million by 2035, exhibiting a growth rate (CAGR) of 7.63% during 2025-2035.
Report Attribute
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Key Statistics
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---|---|
Base Year | 2024 |
Forecast Years | 2025-2035 |
Historical Years |
2019-2024
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Market Size in 2024
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USD 11.9 Million |
Market Forecast in 2035
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USD 26.5 Million |
Market Growth Rate 2025-2035
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7.63% |
The alkaptonuria market has been comprehensively analyzed in IMARC's new report titled "Alkaptonuria Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035". Alkaptonuria, often known as black urine disease, is a rare inherited disorder in which the body is not able to completely metabolize two amino acids (protein building blocks) called tyrosine and phenylalanine. It leads to a body buildup of a substance called homogentisic acid (HGA). This darkens urine and other areas of the body, leading to a range of health complications over time. Ochronosis, an accumulation of dark (blue-black) pigment in certain tissues, is a typical feature of alkaptonuria. The initial presentation of the disease is often black or dark urine on exposure to air (oxidation). However, the color change may not occur immediately after urine. Ochronosis affects connective tissues throughout the body, including the joints, tendons, and ligaments. Pigment changes are easily visible in the whites of the eyes (sclera), the outer ears, and the palms. The diagnostic evaluation of this condition is based on a combination of clinical observation, medical history review, and physical examination. The healthcare professional might also recommend imaging techniques, like CT scans or MRIs, to help assess the severity of joint involvement.
The escalating prevalence of the mutations in the HGD gene, which leads to a deficiency in the enzyme homogentisate 1,2-dioxygenase, crucial for breaking down HGA, is primarily driving the alkaptonuria market. In addition to this, the inflating utilization of anti-inflammatory medications, such as ibuprofen and naproxen to help relieve joint swelling, stiffness, and pain in patients, is also creating a positive outlook for the market. Moreover, the widespread adoption of physical therapy on account of its numerous advantages, like improved posture and spinal alignment, enhanced daily function, and reduced strain on affected joints, is further bolstering the market growth. Apart from this, the rising usage of total joint replacement, since it involves replacing the damaged joint with an artificial joint (prosthesis) made of metal, plastic, or ceramic, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of gene therapy, which aims to replace or correct the defective HGD gene, thereby allowing the body to produce the necessary enzyme and prevent HGA accumulation is expected to drive the alkaptonuria market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the alkaptonuria market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for alkaptonuria and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the alkaptonuria market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
Competitive Landscape:
This report also provides a detailed analysis of the current alkaptonuria marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Key Questions Answered in this Report:
Market Insights
Epidemiology Insights
Alkaptonuria: Current Treatment Scenario, Marketed Drugs and Emerging Therapies