The global bone graft and substitutes market was worth US$ 2.7 Billion in 2019. Bone graft and substitutes are utilized for replacing missing bones or repairing bone fractures. They comprise an osteoconductive matrix that acts as a filler to promote wound healing; osteoinductive proteins which support mitogenesis of identical bone cells; and osteogenic cells that form the bone in the appropriate environment. They are bioresorbable in nature and cause no antigen-antibody reaction. Owing to these attributes, they are widely used for healing fractures and bone injuries, and in spinal, facial, foot, ankle or trauma surgeries.
One of the key trends witnessed in the market is the advent of new polymer and ceramic products that have biologically superior characteristics. The introduction of new manufacturing technologies, such as rapid prototyping or 3D printing, is also helping in the fabrication of free-form biomaterial scaffolds for tissue regeneration. Additionally, the demand for bone graft and substitutes is increasing owing to high morbidity rates, growing geriatric population and the increasing cases of osteoarthritis. Apart from this, a shift towards minimally invasive procedures, coupled with the growing awareness among patients about the benefits of bone regeneration through biologics is further strengthening the market growth. Some of the other growth-inducing factors include the availability of advanced products in different shapes and sizes, rising prevalence of orthopedic problems and periodontal diseases, and increasing number of studies for investigating the enhancement of bioactivity of bone graft substitutes. Looking forward, IMARC Group expects the global bone graft and substitutes market to exhibit moderate growth during the next five years.
The report has also analysed the competitive landscape of the market with some of the key players being Zimmer Biomet Dental, DePuy Synthes, Wright Medical Technology, Medtronic Plc., Stryker Corporation, NuVasive Inc., Arthrex Inc., Integra LifeSciences, Baxter International Inc., Musculoskeletal Transplant Foundation, Bacterin International Holdings, SeaSpine, LifeNet Health, etc.
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