Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035

Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035

Report Format: PDF+Excel | Report ID: SR112025A6383

Market Overview:

The chimeric antigen receptor (CAR) T-cell therapy market reached a value of USD 3,979.2 Million across the top 7 markets (US, EU4, UK, and Japan) in 2024. Looking forward, IMARC Group expects the top 7 major markets to reach USD 12,526.3 Million by 2035, exhibiting a growth rate (CAGR) of 11% during 2025-2035.

Report Attribute
Key Statistics
Base Year  2024
Forecast Years  2025-2035
Historical Years  2019-2024
Market Size in 2024
USD 3,979.2 Million
Market Forecast in 2035
USD 12,526.3 Million
Market Growth Rate 2025-2035
11%


The chimeric antigen receptor (CAR) T-cell therapy market has been comprehensively analyzed in IMARC's new report titled "Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035". CAR T-cell therapy is a cutting-edge form of immunotherapy that involves modifying a patient's T cells to recognize and attack cancer cells. The process begins with collecting T cells from the patient’s blood, followed by genetic engineering to introduce a chimeric antigen receptor (CAR) that targets a specific protein found on cancer cells. These engineered T cells are then multiplied in the laboratory and infused back into the patient, where they actively seek out and destroy cancer cells bearing the target antigen. This personalized approach has shown significant success, particularly in treating certain types of blood cancers such as acute lymphoblastic leukemia and large B-cell lymphoma. By leveraging the body’s immune system in a targeted and potent way, CAR T-cell therapy represents a transformative advancement in cancer treatment. Its highly specific mechanism of action and durable response potential have positioned it as a promising therapeutic option in the rapidly evolving field of oncology.

Chimeric Antigen Receptor (CAR) T-Cell Therapy Market

The Chimeric Antigen Receptor (CAR) T-Cell Therapy market is currently driven by factors such as the rising incidence of cancer, a strong drug pipeline, a rising number of healthcare settings that administer CAR T, improving safety and efficacy of current and emerging therapies, etc. CAR T-cell therapies can potentially transform cancer treatment by using the immune system to fight diseases. CAR T therapy requires genetically engineering T cells (either a patient’s own or a donor’s) to express a chimeric antigen receptor that targets a particular tumor antigen. The biggest factor catalyzing the growth of the market is the strong efficacy of these treatments. For instance, pediatric and young adult patients with relapsed or refractory Acute Lymphoblastic Leukemia (ALL) achieved an overall remission rate of 90 percent during the first 12 months with treatment with an anti-CD19 autologous CAR T therapy. However, despite the convincing efficacy data in clinical trials, there are several challenges impacting the commercialization of CAR-Ts. These challenges include complex and costly manufacturing and supply chain, lengthy and logistically challenging patient journey, and reimbursement challenges. The CAR T-Cell Therapy market is set to be a transformative therapy in cancer care, but unleashing its potential will require placing strategic bets. Technological advances and manufacturing innovations are rapidly improving, with the prospects for CAR T to not only treat niche liquid tumors but a broader range of solid and liquid tumors shortly. Market players that can make intelligent investments can significantly expand the number of patients they treat as well as the success rates of their therapies.

IMARC Group's new report provides an exhaustive analysis of the chimeric antigen receptor (CAR) T-cell therapy market in the United States, EU4 (Germany, Spain, Italy, and France), United Kingdom, and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report, the United States has the largest patient pool for chimeric antigen receptor (CAR) T-cell therapy and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario, unmet medical needs, etc., have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the chimeric antigen receptor (CAR) T-cell therapy market in any manner.

Time Period of the Study

  • Base Year: 2024
  • Historical Period: 2019-2024
  • Market Forecast: 2025-2035

Countries Covered

  • United States
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Japan

Analysis Covered Across Each Country

  • Historical, current, and future epidemiology scenario
  • Historical, current, and future performance of the Chimeric Antigen Receptor (CAR) T-cell Therapy Market
  • Historical, current, and future performance of various therapeutic categories in the market
  • Sales of various drugs across the chimeric antigen receptor (CAR) T-cell therapy market
  • Reimbursement scenario in the market
  • In-market and pipeline drugs

Competitive Landscape:

This report also provides a detailed analysis of the current chimeric antigen receptor (CAR) T-cell therapy marketed drugs and late-stage pipeline drugs.

In-Market Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance
Drugs Company Name
Kymriah (Tisagenlecleucel) Novartis AG
Yescarta (Axicabtagene Ciloleucel) Gilead Sciences, Inc
Tecartus (Brexucabtagene Autoleucel) Gilead Sciences, Inc
Carvykti (Ciltacabtagene Autoleucel) Johnson & Johnson/ Legend Biotech USA Inc
Breyanzi (Lisocabtagene Maraleucel) Bristol Myers Squibb
BAFFR CAR-T (PMB-CT01) PeproMene Bio. Inc
LMY920 Luminary Therapeutics
KYV-101 Kyverna Therapeutics, Inc
NXC-201 Nexcella Inc
CHM-2102 (CDH17) Chimeric Therapeutics Ltd


*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:

Market Insights

  • How has the chimeric antigen receptor (CAR) T-cell therapy market performed so far and how will it perform in the coming years?
  • What are the markets shares of various therapeutic segments in 2024 and how are they expected to perform till 2035?
  • What was the country-wise size of the chimeric antigen receptor (CAR) T-cell therapy across the seven major markets in 2024 and what will it look like in 2035?
  • What is the growth rate of the chimeric antigen receptor (CAR) T-cell therapy across the seven major markets and what will be the expected growth over the next ten years?
  • What are the key unmet needs in the market?

Epidemiology Insights

  • What is the number of incident cases (2019-2035) of chimeric antigen receptor (CAR) T-cell therapy across the seven major markets?
  • What is the number of incident cases (2019-2035) of chimeric antigen receptor (CAR) T-cell therapy by age across the seven major markets?
  • What is the number of incident cases (2019-2035) of chimeric antigen receptor (CAR) T-cell therapy by gender across the seven major markets?
  • What is the number of incident cases (2019-2035) of chimeric antigen receptor (CAR) T-cell therapy by disease type across the seven major markets?
  • How many patients are diagnosed (2019-2035) with chimeric antigen receptor (CAR) T-cell therapy across the seven major markets?
  • What is the size of the chimeric antigen receptor (CAR) T-cell therapy patient pool (2019-2024) across the seven major markets?
  • What would be the forecasted patient pool (2025-2035) across the seven major markets?
  • What are the key factors driving the epidemiological trend of chimeric antigen receptor (CAR) T-cell therapy?
  • What will be the growth rate of patients across the seven major markets?

Chimeric Antigen Receptor (CAR) T-Cell Therapy: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current marketed drugs and what are their market performance?
  • What are the key pipeline drugs and how are they expected to perform in the coming years?
  • How safe are the current marketed drugs and what are their efficacies?
  • How safe are the late-stage pipeline drugs and what are their efficacies?
  • What are the current treatment guidelines for chimeric antigen receptor (CAR) T-cell therapy drugs across the seven major markets?
  • Who are the key companies in the market and what are their market shares?
  • What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the chimeric antigen receptor (CAR) T-cell therapy market?
  • What are the key regulatory events related to the chimeric antigen receptor (CAR) T-cell therapy market?
  • What is the structure of clinical trial landscape by status related to the chimeric antigen receptor (CAR) T-cell therapy market?
  • What is the structure of clinical trial landscape by phase related to the chimeric antigen receptor (CAR) T-cell therapy market?
  • What is the structure of clinical trial landscape by route of administration related to the chimeric antigen receptor (CAR) T-cell therapy market?

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Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035
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