The chimeric antigen receptor (CAR) T-cell therapy market reached a value of USD 3,979.2 Million across the top 7 markets (US, EU4, UK, and Japan) in 2024. Looking forward, IMARC Group expects the top 7 major markets to reach USD 12,526.3 Million by 2035, exhibiting a growth rate (CAGR) of 11% during 2025-2035.
Report Attribute
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Key Statistics
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Base Year | 2024 |
Forecast Years | 2025-2035 |
Historical Years | 2019-2024 |
Market Size in 2024
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USD 3,979.2 Million
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Market Forecast in 2035
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USD 12,526.3 Million
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Market Growth Rate 2025-2035
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11% |
The chimeric antigen receptor (CAR) T-cell therapy market has been comprehensively analyzed in IMARC's new report titled "Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2025-2035". CAR T-cell therapy is a cutting-edge form of immunotherapy that involves modifying a patient's T cells to recognize and attack cancer cells. The process begins with collecting T cells from the patient’s blood, followed by genetic engineering to introduce a chimeric antigen receptor (CAR) that targets a specific protein found on cancer cells. These engineered T cells are then multiplied in the laboratory and infused back into the patient, where they actively seek out and destroy cancer cells bearing the target antigen. This personalized approach has shown significant success, particularly in treating certain types of blood cancers such as acute lymphoblastic leukemia and large B-cell lymphoma. By leveraging the body’s immune system in a targeted and potent way, CAR T-cell therapy represents a transformative advancement in cancer treatment. Its highly specific mechanism of action and durable response potential have positioned it as a promising therapeutic option in the rapidly evolving field of oncology.
The Chimeric Antigen Receptor (CAR) T-Cell Therapy market is currently driven by factors such as the rising incidence of cancer, a strong drug pipeline, a rising number of healthcare settings that administer CAR T, improving safety and efficacy of current and emerging therapies, etc. CAR T-cell therapies can potentially transform cancer treatment by using the immune system to fight diseases. CAR T therapy requires genetically engineering T cells (either a patient’s own or a donor’s) to express a chimeric antigen receptor that targets a particular tumor antigen. The biggest factor catalyzing the growth of the market is the strong efficacy of these treatments. For instance, pediatric and young adult patients with relapsed or refractory Acute Lymphoblastic Leukemia (ALL) achieved an overall remission rate of 90 percent during the first 12 months with treatment with an anti-CD19 autologous CAR T therapy. However, despite the convincing efficacy data in clinical trials, there are several challenges impacting the commercialization of CAR-Ts. These challenges include complex and costly manufacturing and supply chain, lengthy and logistically challenging patient journey, and reimbursement challenges. The CAR T-Cell Therapy market is set to be a transformative therapy in cancer care, but unleashing its potential will require placing strategic bets. Technological advances and manufacturing innovations are rapidly improving, with the prospects for CAR T to not only treat niche liquid tumors but a broader range of solid and liquid tumors shortly. Market players that can make intelligent investments can significantly expand the number of patients they treat as well as the success rates of their therapies.
IMARC Group's new report provides an exhaustive analysis of the chimeric antigen receptor (CAR) T-cell therapy market in the United States, EU4 (Germany, Spain, Italy, and France), United Kingdom, and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report, the United States has the largest patient pool for chimeric antigen receptor (CAR) T-cell therapy and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario, unmet medical needs, etc., have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the chimeric antigen receptor (CAR) T-cell therapy market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current chimeric antigen receptor (CAR) T-cell therapy marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs | Company Name |
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Kymriah (Tisagenlecleucel) | Novartis AG |
Yescarta (Axicabtagene Ciloleucel) | Gilead Sciences, Inc |
Tecartus (Brexucabtagene Autoleucel) | Gilead Sciences, Inc |
Carvykti (Ciltacabtagene Autoleucel) | Johnson & Johnson/ Legend Biotech USA Inc |
Breyanzi (Lisocabtagene Maraleucel) | Bristol Myers Squibb |
BAFFR CAR-T (PMB-CT01) | PeproMene Bio. Inc |
LMY920 | Luminary Therapeutics |
KYV-101 | Kyverna Therapeutics, Inc |
NXC-201 | Nexcella Inc |
CHM-2102 (CDH17) | Chimeric Therapeutics Ltd |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Chimeric Antigen Receptor (CAR) T-Cell Therapy: Current Treatment Scenario, Marketed Drugs and Emerging Therapies