Market Overview:
The global downstream processing market is expected to exhibit a CAGR of 14.67% during 2022-2027. Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.
Downstream processing refers to the purification and recovery of biosynthetic and pharmaceutical products extracted from natural sources. The sources include plant and animal tissues that can be recycled and treated. Downstream processing involves solid-liquid separation, release of intracellular products, chromatography purification and formulation. These processes are conducted through floatation, flocculation, centrifugation and filtration and are used for the manufacturing of anti-infection agents, antibiotics, antibodies, hormones, vaccines and industrial enzymes. Downstream processing also aids in maximizing product recovery and minimizing the overall cost of production.
Significant growth in the pharmaceutical industry across the globe is one of the key factors creating a positive outlook for the market. Downstream processing is widely used for isolating, purifying and concentrating the synthesized drug substances from the complex bulk matrix. Furthermore, the increasing prevalence of various infectious diseases, such as dengue, hepatitis and swine influenza, is providing a thrust to the market growth. As the coronavirus disease (COVID-19) continues to spread, there has been a substantial increase in the utilization of downstream processing for the manufacturing of vaccines with higher efficacy and minimal side-effects. Additionally, various technological advancements, such as the development of innovative multicomponent separation and perfusion chromatography systems, are acting as other growth-inducing factors. These solutions are widely utilized for the purification of recombinant protein produced by animal cell cultures to create high-value products. Other factors, including extensive research and development (R&D) activities in the field of biochemical engineering, along with significant improvements in the healthcare infrastructure, especially in the developing nations, are anticipated to drive the market toward growth.
Key Market Segmentation:
IMARC Group provides an analysis of the key trends in each sub-segment of the global downstream processing market report, along with forecasts at the global, regional and country level from 2022-2027. Our report has categorized the market based on technique, product, application and end use.
Breakup by Technique:
- Solid-Liquid Separation
- Cell Disruption
- Concentration
- Purification by Chromatography
- Formulation
Breakup by Product:
- Chromatography Systems
- Filters
- Evaporators
- Centrifuges
- Dryers
- Others
Breakup by Application:
- Antibiotic Production
- Hormone Production
- Antibodies Production
- Enzyme Production
- Vaccine Production
- Others
Breakup by End Use:
- Biopharmaceutical Companies
- Contract Manufacturing Organizations
Breakup by Region:
- North America
- Asia-Pacific
- China
- Japan
- India
- South Korea
- Australia
- Indonesia
- Others
- Europe
- Germany
- France
- United Kingdom
- Italy
- Spain
- Russia
- Others
- Latin America
- Middle East and Africa
Competitive Landscape:
The competitive landscape of the industry has also been examined along with the profiles of the key players being 3M Company, Boehringer Ingelheim International GmbH, Corning Corporation, Danaher Corporation, Eppendorf AG, Lonza Group AG, Merck KGaA, Repligen Corporation, Sartorius AG and Thermo Fisher Scientific Inc.
Report Coverage:
| Report Features |
Details |
|---|
| Base Year of the Analysis |
2021 |
| Historical Period |
2016-2021 |
| Forecast Period |
2022-2027 |
| Units |
US$ Billion |
| Segment Coverage |
Technique, Product, Application, End Use, Region |
| Region Covered |
Asia Pacific, Europe, North America, Latin America, Middle East and Africa |
| Countries Covered |
United States, Canada, Germany, France, United Kingdom, Italy, Spain, Russia, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico |
| Companies Covered |
3M Company, Boehringer Ingelheim International GmbH, Corning Corporation, Danaher Corporation, Eppendorf AG, Lonza Group AG, Merck KGaA, Repligen Corporation, Sartorius AG and Thermo Fisher Scientific Inc. |
| Customization Scope |
10% Free Customization |
| Report Price and Purchase Option |
Single User License: US$ 2499
Five User License: US$ 3499
Corporate License: US$ 4499 |
| Post-Sale Analyst Support |
10-12 Weeks |
| Delivery Format |
PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request) |
Key Questions Answered in This Report:
- How has the global downstream processing market performed so far and how will it perform in the coming years?
- What has been the impact of COVID-19 on the global downstream processing market?
- What are the key regional markets?
- What is the breakup of the market based on the technique?
- What is the breakup of the market based on the product?
- What is the breakup of the market based on the application?
- What is the breakup of the market based on the end use?
- What are the various stages in the value chain of the industry?
- What are the key driving factors and challenges in the industry?
- What is the structure of the global downstream processing market and who are the key players?
- What is the degree of competition in the industry?
1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
4.1 Overview
4.2 Key Industry Trends
5 Global Downstream Processing Market
5.1 Market Overview
5.2 Market Performance
5.3 Impact of COVID-19
5.4 Market Forecast
6 Market Breakup by Technique
6.1 Solid-Liquid Separation
6.1.1 Market Trends
6.1.2 Market Forecast
6.2 Cell Disruption
6.2.1 Market Trends
6.2.2 Market Forecast
6.3 Concentration
6.3.1 Market Trends
6.3.2 Market Forecast
6.4 Purification by Chromatography
6.4.1 Market Trends
6.4.2 Market Forecast
6.5 Formulation
6.5.1 Market Trends
6.5.2 Market Forecast
7 Market Breakup by Product
7.1 Chromatography Systems
7.1.1 Market Trends
7.1.2 Market Forecast
7.2 Filters
7.2.1 Market Trends
7.2.2 Market Forecast
7.3 Evaporators
7.3.1 Market Trends
7.3.2 Market Forecast
7.4 Centrifuges
7.4.1 Market Trends
7.4.2 Market Forecast
7.5 Dryers
7.5.1 Market Trends
7.5.2 Market Forecast
7.6 Others
7.6.1 Market Trends
7.6.2 Market Forecast
8 Market Breakup by Application
8.1 Antibiotic Production
8.1.1 Market Trends
8.1.2 Market Forecast
8.2 Hormone Production
8.2.1 Market Trends
8.2.2 Market Forecast
8.3 Antibodies Production
8.3.1 Market Trends
8.3.2 Market Forecast
8.4 Enzyme Production
8.4.1 Market Trends
8.4.2 Market Forecast
8.5 Vaccine Production
8.5.1 Market Trends
8.5.2 Market Forecast
8.6 Others
8.6.1 Market Trends
8.6.2 Market Forecast
9 Market Breakup by End Use
9.1 Biopharmaceutical Companies
9.1.1 Market Trends
9.1.2 Market Forecast
9.2 Contract Manufacturing Organizations
9.2.1 Market Trends
9.2.2 Market Forecast
10 Market Breakup by Region
10.1 North America
10.1.1 United States
10.1.1.1 Market Trends
10.1.1.2 Market Forecast
10.1.2 Canada
10.1.2.1 Market Trends
10.1.2.2 Market Forecast
10.2 Asia-Pacific
10.2.1 China
10.2.1.1 Market Trends
10.2.1.2 Market Forecast
10.2.2 Japan
10.2.2.1 Market Trends
10.2.2.2 Market Forecast
10.2.3 India
10.2.3.1 Market Trends
10.2.3.2 Market Forecast
10.2.4 South Korea
10.2.4.1 Market Trends
10.2.4.2 Market Forecast
10.2.5 Australia
10.2.5.1 Market Trends
10.2.5.2 Market Forecast
10.2.6 Indonesia
10.2.6.1 Market Trends
10.2.6.2 Market Forecast
10.2.7 Others
10.2.7.1 Market Trends
10.2.7.2 Market Forecast
10.3 Europe
10.3.1 Germany
10.3.1.1 Market Trends
10.3.1.2 Market Forecast
10.3.2 France
10.3.2.1 Market Trends
10.3.2.2 Market Forecast
10.3.3 United Kingdom
10.3.3.1 Market Trends
10.3.3.2 Market Forecast
10.3.4 Italy
10.3.4.1 Market Trends
10.3.4.2 Market Forecast
10.3.5 Spain
10.3.5.1 Market Trends
10.3.5.2 Market Forecast
10.3.6 Russia
10.3.6.1 Market Trends
10.3.6.2 Market Forecast
10.3.7 Others
10.3.7.1 Market Trends
10.3.7.2 Market Forecast
10.4 Latin America
10.4.1 Brazil
10.4.1.1 Market Trends
10.4.1.2 Market Forecast
10.4.2 Mexico
10.4.2.1 Market Trends
10.4.2.2 Market Forecast
10.4.3 Others
10.4.3.1 Market Trends
10.4.3.2 Market Forecast
10.5 Middle East and Africa
10.5.1 Market Trends
10.5.2 Market Breakup by Country
10.5.3 Market Forecast
11 SWOT Analysis
11.1 Overview
11.2 Strengths
11.3 Weaknesses
11.4 Opportunities
11.5 Threats
12 Value Chain Analysis
13 Porters Five Forces Analysis
13.1 Overview
13.2 Bargaining Power of Buyers
13.3 Bargaining Power of Suppliers
13.4 Degree of Competition
13.5 Threat of New Entrants
13.6 Threat of Substitutes
14 Price Analysis
15 Competitive Landscape
15.1 Market Structure
15.2 Key Players
15.3 Profiles of Key Players
15.3.1 3M Company
15.3.1.1 Company Overview
15.3.1.2 Product Portfolio
15.3.1.3 Financials
15.3.1.4 SWOT Analysis
15.3.2 Boehringer Ingelheim International GmbH
15.3.2.1 Company Overview
15.3.2.2 Product Portfolio
15.3.3 Corning Corporation
15.3.3.1 Company Overview
15.3.3.2 Product Portfolio
15.3.3.3 Financials
15.3.3.4 SWOT Analysis
15.3.4 Danaher Corporation
15.3.4.1 Company Overview
15.3.4.2 Product Portfolio
15.3.4.3 Financials
15.3.4.4 SWOT Analysis
15.3.5 Eppendorf AG
15.3.5.1 Company Overview
15.3.5.2 Product Portfolio
15.3.5.3 SWOT Analysis
15.3.6 Lonza Group AG
15.3.6.1 Company Overview
15.3.6.2 Product Portfolio
15.3.6.3 Financials
15.3.6.4 SWOT Analysis
15.3.7 Merck KGaA
15.3.7.1 Company Overview
15.3.7.2 Product Portfolio
15.3.7.3 Financials
15.3.7.4 SWOT Analysis
15.3.8 Repligen Corporation
15.3.8.1 Company Overview
15.3.8.2 Product Portfolio
15.3.8.3 Financials
15.3.9 Sartorius AG
15.3.9.1 Company Overview
15.3.9.2 Product Portfolio
15.3.9.3 Financials
15.3.9.4 SWOT Analysis
15.3.10 Thermo Fisher Scientific Inc.
15.3.10.1 Company Overview
15.3.10.2 Product Portfolio
15.3.10.3 Financials
15.3.10.4 SWOT Analysis
List of Figures
Figure 1: Global: Downstream Processing Market: Major Drivers and Challenges
Figure 2: Global: Downstream Processing Market: Sales Value (in Billion US$), 2016-2021
Figure 3: Global: Downstream Processing Market Forecast: Sales Value (in Billion US$), 2022-2027
Figure 4: Global: Downstream Processing Market: Breakup by Technique (in %), 2021
Figure 5: Global: Downstream Processing Market: Breakup by Product (in %), 2021
Figure 6: Global: Downstream Processing Market: Breakup by Application (in %), 2021
Figure 7: Global: Downstream Processing Market: Breakup by End Use (in %), 2021
Figure 8: Global: Downstream Processing Market: Breakup by Region (in %), 2021
Figure 9: Global: Downstream Processing (Solid-Liquid Separation) Market: Sales Value (in Million US$), 2016 & 2021
Figure 10: Global: Downstream Processing (Solid-Liquid Separation) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 11: Global: Downstream Processing (Cell Disruption) Market: Sales Value (in Million US$), 2016 & 2021
Figure 12: Global: Downstream Processing (Cell Disruption) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 13: Global: Downstream Processing (Concentration) Market: Sales Value (in Million US$), 2016 & 2021
Figure 14: Global: Downstream Processing (Concentration) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 15: Global: Downstream Processing (Purification by Chromatography) Market: Sales Value (in Million US$), 2016 & 2021
Figure 16: Global: Downstream Processing (Purification by Chromatography) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 17: Global: Downstream Processing (Formulation) Market: Sales Value (in Million US$), 2016 & 2021
Figure 18: Global: Downstream Processing (Formulation) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 19: Global: Downstream Processing (Chromatography Systems) Market: Sales Value (in Million US$), 2016 & 2021
Figure 20: Global: Downstream Processing (Chromatography Systems) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 21: Global: Downstream Processing (Filters) Market: Sales Value (in Million US$), 2016 & 2021
Figure 22: Global: Downstream Processing (Filters) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 23: Global: Downstream Processing (Evaporators) Market: Sales Value (in Million US$), 2016 & 2021
Figure 24: Global: Downstream Processing (Evaporators) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 25: Global: Downstream Processing (Centrifuges) Market: Sales Value (in Million US$), 2016 & 2021
Figure 26: Global: Downstream Processing (Centrifuges) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 27: Global: Downstream Processing (Dryers) Market: Sales Value (in Million US$), 2016 & 2021
Figure 28: Global: Downstream Processing (Dryers) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 29: Global: Downstream Processing (Other Products) Market: Sales Value (in Million US$), 2016 & 2021
Figure 30: Global: Downstream Processing (Other Products) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 31: Global: Downstream Processing (Antibiotic Production) Market: Sales Value (in Million US$), 2016 & 2021
Figure 32: Global: Downstream Processing (Antibiotic Production) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 33: Global: Downstream Processing (Hormone Production) Market: Sales Value (in Million US$), 2016 & 2021
Figure 34: Global: Downstream Processing (Hormone Production) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 35: Global: Downstream Processing (Antibodies Production) Market: Sales Value (in Million US$), 2016 & 2021
Figure 36: Global: Downstream Processing (Antibodies Production) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 37: Global: Downstream Processing (Enzyme Production) Market: Sales Value (in Million US$), 2016 & 2021
Figure 38: Global: Downstream Processing (Enzyme Production) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 39: Global: Downstream Processing (Vaccine Production) Market: Sales Value (in Million US$), 2016 & 2021
Figure 40: Global: Downstream Processing (Vaccine Production) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 41: Global: Downstream Processing (Other Applications) Market: Sales Value (in Million US$), 2016 & 2021
Figure 42: Global: Downstream Processing (Other Applications) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 43: Global: Downstream Processing (Biopharmaceutical Companies) Market: Sales Value (in Million US$), 2016 & 2021
Figure 44: Global: Downstream Processing (Biopharmaceutical Companies) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 45: Global: Downstream Processing (Contract Manufacturing Organizations) Market: Sales Value (in Million US$), 2016 & 2021
Figure 46: Global: Downstream Processing (Contract Manufacturing Organizations) Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 47: North America: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 48: North America: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 49: United States: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 50: United States: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 51: Canada: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 52: Canada: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 53: Asia-Pacific: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 54: Asia-Pacific: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 55: China: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 56: China: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 57: Japan: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 58: Japan: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 59: India: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 60: India: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 61: South Korea: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 62: South Korea: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 63: Australia: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 64: Australia: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 65: Indonesia: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 66: Indonesia: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 67: Others: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 68: Others: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 69: Europe: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 70: Europe: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 71: Germany: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 72: Germany: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 73: France: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 74: France: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 75: United Kingdom: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 76: United Kingdom: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 77: Italy: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 78: Italy: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 79: Spain: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 80: Spain: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 81: Russia: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 82: Russia: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 83: Others: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 84: Others: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 85: Latin America: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 86: Latin America: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 87: Brazil: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 88: Brazil: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 89: Mexico: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 90: Mexico: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 91: Others: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 92: Others: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 93: Middle East and Africa: Downstream Processing Market: Sales Value (in Million US$), 2016 & 2021
Figure 94: Middle East and Africa: Downstream Processing Market: Breakup by Country (in %), 2021
Figure 95: Middle East and Africa: Downstream Processing Market Forecast: Sales Value (in Million US$), 2022-2027
Figure 96: Global: Downstream Processing Industry: SWOT Analysis
Figure 97: Global: Downstream Processing Industry: Value Chain Analysis
Figure 98: Global: Downstream Processing Industry: Porter's Five Forces Analysis
List of Tables
Table 1: Global: Downstream Processing Market: Key Industry Highlights, 2021 and 2027
Table 2: Global: Downstream Processing Market Forecast: Breakup by Technique (in Million US$), 2022-2027
Table 3: Global: Downstream Processing Market Forecast: Breakup by Product (in Million US$), 2022-2027
Table 4: Global: Downstream Processing Market Forecast: Breakup by Application (in Million US$), 2022-2027
Table 5: Global: Downstream Processing Market Forecast: Breakup by End Use (in Million US$), 2022-2027
Table 6: Global: Downstream Processing Market Forecast: Breakup by Region (in Million US$), 2022-2027
Table 7: Global: Downstream Processing Market: Competitive Structure
Table 8: Global: Downstream Processing Market: Key Players