Methadone Market Report by Modes of Administration (Oral Medicine, Injections), Therapeutic Area (Pain Treatment, Detoxification, Maintenance Therapy), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Rehab Centers, Drug Stores), and Region 2023-2028

Methadone Market Report by Modes of Administration (Oral Medicine, Injections), Therapeutic Area (Pain Treatment, Detoxification, Maintenance Therapy), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Rehab Centers, Drug Stores), and Region 2023-2028

Report Format: PDF+Excel | Report ID: SR112023A12366
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Market Overview:

The global methadone market size reached US$ 120.0 Million in 2022. Looking forward, IMARC Group expects the market to reach US$ 166.0 Million by 2028, exhibiting a growth rate (CAGR) of 5.5% during 2023-2028. The increasing number of patients associated with therapeutics pain treatment, rising concerns about the side effects of narcotics drugs, and the growing adoption for safer pregnancy management are some of the major factors propelling the market growth.

Report Attribute
Key Statistics
Base Year
Forecast Years
Historical Years
Market Size in 2022 US$ 120.0 Million
Market Forecast in 2028 US$ 166.0 Million
Market Growth Rate (2023-2028) 5.5%

Methadone is a synthetic opioid medication primarily used for the treatment of opioid dependence and chronic pain. It belongs to the class of opioid drugs comprising substances like heroin, morphine, and oxycodone. It works by relieving withdrawal symptoms without producing the intense euphoria or high associated with other opioids. It can provide analgesic effects or when other opioids are ineffective or not well-tolerated. It is utilized as a substitute for other opioids to help individuals manage withdrawal symptoms and reduce cravings.

The increasing number of people undergoing therapeutics pain treatment and suffering from cancer, multiple sclerosis (MS), and other chronic disorder pain is favoring the growth of the market. Moreover, rising concerns about the side effects of narcotics drugs are catalyzing the demand for methadone drugs. This, coupled with the increasing awareness among individuals about the benefits and effectiveness of methadone treatment, is strengthening the growth of the market. In addition, the growing adoption of methadone treatment for managing opioid dependence during pregnancy as compared to illicit drug use, which reduces potential harm to the fetus, is influencing the market positively. Apart from this, the integration of methadone treatment in primary care settings to improve accessibility encourages comprehensive care and reduce fragmentation of services is propelling the growth of the market.

Methadone Market Trends/Drivers:

Increasing incidences of opioid overdose impelling the market growth

Opioid addiction has reached alarming levels around the world. This, along with the growing number of individuals struggling with substance abuse, represents one of the key factors impelling the growth of the market. Methadone, a medication used for opioid dependence treatment, has proven effective in reducing withdrawal symptoms and cravings, enabling individuals to regain control of their lives. As the crisis intensifies, the demand for evidence-based addiction treatment has increased, which led to a rise in the need for methadone clinics and programs. Governments, healthcare providers, and communities recognize the urgency of addressing this public health crisis, which is resulting in the expanding access to methadone maintenance treatment. Furthermore, the effectiveness of methadone in preventing overdose deaths has garnered attention worldwide, as it can be a life-saving intervention. The rising awareness of the opioid epidemic devastating impact and the desire to provide effective treatment options are primary factors driving the demand for methadone.

Rising demand for personalized treatment approach catalyzing the demand for methadone

Methadone treatment offers a personalized and individualized approach to address opioid addiction. The journey of recovery is unique for everyone, and methadone dosage can be tailored according to individual needs. Healthcare providers can adjust the dosage and monitor progress to optimize the effectiveness of the treatment for each patient. This customization helps ensure that individuals receive an appropriate and tailored intervention based on their specific circumstances, medical history, and treatment goals. Methadone treatment plans can also be adapted over time to accommodate changes in the needs of an individual, which allows for ongoing support and adjustments as required. The ability to provide personalized care and adapt treatment plans makes methadone an appealing option for individuals seeking addiction treatment and contributes to the growing demand for this tailored approach to address opioid dependence.

Easy accessibility and availability of methadone bolstering market growth

The expansion of methadone treatment offering methadone prescriptions has made it more accessible to individuals seeking recovery from opioid addiction. Governments, healthcare organizations, and advocacy groups have recognized the importance of increasing access to evidence-based treatments, including methadone. Efforts to remove barriers, such as reducing waiting times, improving insurance coverage, and integrating methadone treatment into mainstream healthcare settings, have all contributed to increased availability. Additionally, the development of alternative forms of methadone, such as oral solutions and dissolvable tablets, has enhanced convenience and improved access for patients. Individuals can access the treatment they need by making methadone more accessible and readily available, which leads to a higher demand for this evidence-based intervention in the management of opioid addiction.

Methadone Industry Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the global methadone market report, along with forecasts at the global, regional and country levels for 2023-2028. Our report has categorized the market based on mode of administration, therapeutic area, and distribution channel.

Breakup by Mode of Administration:

  • Oral Medicine
  • Injections

Oral medicine represents the commonly used mode of administration

The report has provided a detailed breakup and analysis of the methadone market based on the mode of administration. This includes oral medicine and injections. According to the report, oral medicine represented the largest segment as it is taken by mouth and gets absorbed through the digestive system. The dosage and frequency of methadone administration are determined by healthcare professionals based on individual needs and treatment plans.

Methadone can also be administered through injections, although this mode of administration is less common. Injectable methadone is used in clinical or hospital settings, wherein healthcare professionals can administer the medication directly into muscles or veins of patients. Injectable methadone is not commonly used for routine maintenance treatment of opioid dependence and is typically reserved for specific situations wherein oral administration is not feasible or appropriate.

Breakup by Therapeutic Area:

  • Pain Treatment
  • Detoxification
  • Maintenance Therapy

Pain treatment dominates the overall market

The report has provided a detailed breakup and analysis of the methadone market based on the therapeutic area. This includes pain treatment, detoxification, and maintenance therapy. According to the report, pain treatment represented the largest segment. Methadone is prescribed by healthcare professionals to manage moderate to severe chronic pain that is not adequately controlled by other pain medications. It is particularly useful for patients who have developed tolerance to other opioids or have experienced inadequate pain relief with other analgesics. Its long duration of action allows for less frequent dosing, which makes it beneficial for patients requiring round-the-clock pain management.

It is also used for detoxification or withdrawal management in individuals with opioid dependence. It helps alleviate the uncomfortable symptoms associated with opioid withdrawal, such as cravings, anxiety, muscle aches, and insomnia. It is utilized in detoxification programs to gradually reduce and eliminate the dependence on opioids and provide a more controlled and manageable withdrawal process.

Breakup by Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Rehab Centers
  • Drug Stores

Methadone is widely sold via rehab centers

The report has provided a detailed breakup and analysis of the methadone market based on the distribution channel. This includes hospital pharmacies, retail pharmacies, rehab centers, and drug stores. According to the report, rehab centers represented the largest segment. Rehab centers provide a holistic approach to addiction treatment by combining medical interventions with counseling, therapy, and support services. They can tailor methadone dosages and treatment plans to the specific needs of each patient, which ensures optimal outcomes in the context of substance abuse treatment. They offer a supportive and structured environment conducive to recovery, with access to a multidisciplinary team of healthcare professionals and peer support.

Hospital pharmacies have pharmacists and healthcare professionals with specialized knowledge and experience in managing complex medication regimens. They can provide valuable guidance and support in the appropriate use of methadone, especially in the context of pain management or detoxification within a hospital setting. They have a steady supply of methadone, which ensures that patients in need can access the medication promptly. They are integrated into the healthcare system, which allows for seamless coordination between different healthcare providers involved in a patient's treatment.

Breakup by Region:

  • North America
    • United States
    • Canada
  • Europe
    • Germany
    • France
    • United Kingdom
    • Italy
    • Spain
    • Others
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Indonesia
    • Others
  • Latin America
    • Brazil
    • Mexico
    • Others
  • Middle East and Africa


North America exhibits a clear dominance, accounting for the largest methadone market share

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa.

North America held the biggest market share due to the increasing prevalence of opioid addiction. Moreover, governing agencies of numerous countries in the region are undertaking initiatives to expand access to addiction treatment, such as methadone. Besides this, the growing number of overdose deaths is catalyzing the demand for methadone as a life-saving intervention in the region.

Asia Pacific is estimated to expand further in this domain on account of the rising opioid use, easy availability, and expansion of healthcare industry in the region.

Competitive Landscape:

The top companies in the global methadone market are focusing on incorporating electronic health records (EHR) that allow for accurate and secure digital documentation of patient information, treatment plans, medication dosages, and progress. This advancement also facilitates better communication and coordination between healthcare providers, ensuring comprehensive and integrated care. Moreover, there is an increase in the adoption of telemedicine technologies to enable remote consultations between healthcare providers and patients. It can be used for initial assessments, follow-up visits, and medication management. Remote monitoring tools, such as mobile apps or wearable devices, can track patient adherence to methadone treatment, provide reminders, and collect data for healthcare professionals to assess progress. Besides this, there is a rise in the installation of automated dispensing systems, such as medication vending machines or robotic dispensers that help accurately dispense methadone doses, which reduces the risk of errors and streamlines the process. They also provide enhanced security and inventory control.

The report has provided a comprehensive analysis of the competitive landscape in the global methadone market. Detailed profiles of all major companies have also been provided. Some of the key players in the market include: 

  • Mallinckrodt Pharmaceuticals
  • Hikma Pharmaceuticals PLC
  • VistaPharm Inc. (Pharmaceutical Associates Inc.)

Recent Developments:

  • In February 2022, VistaPharm Inc. (Pharmaceutical Associates Inc.) expanded its portfolio with Teligent Sterile Injectable and Topical Products.
  • In April 2022, Hikma Labs Inc. acquired US-based generic sterile injectables company Custopharm from Water Street Healthcare Partners in a deal valued at $425m.
  • In 2019, Mallinckrodt Pharmaceuticals and Silence Therapeutics announced a collaboration to launch and commercialize RNAi therapeutics for complement-mediated disorders.

Methadone Market Report Scope:

Report Features Details
Base Year of the Analysis 2022
 Historical Period 2017-2022
Forecast Period 2023-2028
Units US$ Million
Scope of the Report Exploration of Historical and Forecast Trends, Industry Catalysts and Challenges, Segment-Wise Historical and Predictive Market Assessment: 
  • Mode of Administration
  • Therapeutic Area
  • Distribution Channel
  • Region
Modes of Administration Covered Oral Medicine, Injections
Therapeutic Areas Covered Pain Treatment, Detoxification, Maintenance Therapy
Distribution Channels Covered Hospital Pharmacies, Retail Pharmacies, Rehab Centers, Drug Stores
Regions Covered Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered United States, Canada, Germany, France, United Kingdom, Italy, Spain, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered Mallinckrodt Pharmaceuticals, Hikma Pharmaceuticals PLC., VistaPharm Inc. (Pharmaceutical Associates Inc.), etc.
Customization Scope 10% Free Customization
Report Price and Purchase Option Single User License: US$ 2499
Five User License: US$ 3499
Corporate License: US$ 4499
Post-Sale Analyst Support 10-12 Weeks
Delivery Format PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request)

Key Questions Answered in This Report:

  • How has the global methadone market performed so far, and how will it perform in the coming years?
  • What are the drivers, restraints, and opportunities in the global methadone market?
  • What is the impact of each driver, restraint, and opportunity on the global methadone market?
  • What are the key regional markets?
  • Which countries represent the most attractive methadone market? 
  • What is the breakup of the market based on the mode of administration?
  • Which is the most attractive mode of administration in the methadone market?
  • What is the breakup of the market based on the therapeutic area?
  • Which is the most attractive therapeutic area in the methadone market?
  • What is the breakup of the market based on the distribution channel?
  • Which is the most attractive distribution channel in the methadone market?
  • What is the competitive structure of the global methadone market?
  • Who are the key players/companies in the global methadone market?

Key Benefits for Stakeholders:

  • IMARC’s report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the methadone market from 2017-2028.
  • The research study provides the latest information on the market drivers, challenges, and opportunities in the global methadone market.
  • The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
  • Porter's five forces analysis assist stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the methadone industry and its attractiveness.
  • Competitive landscape allows stakeholders to understand their competitive environment and provides an insight into the current positions of key players in the market.

Need more help?

  • Speak to our experienced analysts for insights on the current market scenarios.
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Methadone Market Report by Modes of Administration (Oral Medicine, Injections), Therapeutic Area (Pain Treatment, Detoxification, Maintenance Therapy), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Rehab Centers, Drug Stores), and Region 2023-2028
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