Rat Model Market

Global Rat Model Market:

The global rat model market size reached USD 1.5 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 2.6 Billion by 2033, exhibiting a growth rate (CAGR) of 6.50% during 2025-2033. The rising demand for personalized medicines is primarily stimulating the market.

Rat Model Market Analysis:

• Major Market Drivers: Extensive R&D activities across the pharmaceutical industry are acting as significant growth-inducing factors.
• Key Market Trends: The increasing occurrence of several viruses causing contagious diseases is positively influencing the market.
• Competitive Landscape: Some of the prominent companies in the global market include Biomere, Charles River Laboratories International Inc., Cyagen Biosciences Inc., Envigo (Inotiv Inc.), genOway S.A., Janvier Labs, Taconic Biosciences Inc., and TransViragen Inc., among many others.
• Geographical Trends: The rising investments in creating novel drugs and vaccines to eradicate life-threatening diseases are contributing to the market in North America.
• Challenges and Opportunities: The lack of generic diversity is one of the challenges hindering the market. However, the development of models with enhanced mimic human pathophysiology is expected to fuel the market over the forecasted period.
   

Rat Model Market Trends:

Growing Demand for Humanized Rat Models

The rising need for more accurate preclinical studies that better predict human responses to therapies and drugs is propelling the market. Humanized models are particularly valuable in immunology, oncology, and infectious disease research. For example, in June 2024, Google’s AI division DeepMind introduced a computerized rat model that is able to move around like a real rodent through an artificial brain.

Increasing Advancements in Genetic Engineering

The growing focus on studying complex diseases, such as diabetes, cancer, and neurological disorders, is elevating the rat model market revenue. For instance, in March 2024, the International Brain pH Project Consortium unveiled findings in a large-scale animal model study that indicate altered brain pH and lactate levels as a transdiagnostic endophenotype in neuropsychiatric disorders with cognitive impairment.

Rising Ethical Research Practices

Researchers are seeking ways to reduce the number of animals used, thereby stimulating the market. In addition, they complement the use of rat models, helping to achieve these ethical goals, which is acting as another significant growth-inducing factor. For example, in April 2024, the NZ Anti-Vivisection Society launched a rat rehoming program with the University of Auckland to rehome rats bred or used for science.

Global Rat Model Industry Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the market, along with the rat model market forecast at the global, regional, and country levels for 2025-2033. Our report has categorized the market based on the model type, technology, service, therapeutic area, and end user.

Breakup by Model Type:

• Outbred Rats
• Inbred Rats
• Knockout/Genetically Modified Rats
• Hybrid/Congenic Rats
• Conditioned/Surgically Modified Rats
• Immunodeficient Rats
   

Outbred rats dominate the market

The report has provided a detailed breakup and analysis of the market based on the model type. This includes outbred rats, inbred rats, knockout/genetically modified rats, hybrid/congenic rats, conditioned/surgically modified rats, and immunodeficient rats. According to the report, outbred rats represented the largest market segmentation. 

Outbred rats are valued in research for their genetic diversity, thereby making them essential for general toxicology studies. For example, Charles River Laboratories introduced their new Sprague Dawley IGS rat, which offers improved genetic monitoring. This is positively influencing the rat model market outlook.

Breakup by Technology:

• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
• Microinjection
• Embryonic Stem Cell Injection
• Nuclear Transfer
• Others
   

Clustered regularly interspaced short palindromic repeats (CRISPR) currently hold most of the total rat model market share

The report has provided a detailed breakup and analysis of the market based on the technology. This includes clustered regularly interspaced short palindromic repeats (CRISPR), microinjection, embryonic stem cell injection, nuclear transfer, and others. According to the report, clustered regularly interspaced short palindromic repeats (CRISPR) represented the largest market segmentation.

Clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized genetic research and therapy. For example, Thermo Fisher Scientific introduced their TrueCut Cas9 Protein v2, which offers reduced off-target effects and higher precision.

Breakup by Service:

• Breeding
• Cryopreservation
• Re-derivation
• Genetic Testing
• Quarantine
• Others
   

The report has provided a detailed breakup and analysis of the market based on the service. This includes breeding, cryopreservation, re-derivation, genetic testing, quarantine, and others.

Breeding services aid in maintaining and expanding specific rat colonies. Cryopreservation services play a crucial role in preserving genetic material. Re-derivation services are also vital for eliminating pathogens. Genetic testing services ensure the accuracy of genetic modifications. On the other hand, quarantine services are necessary to prevent the introduction of diseases into research facilities.

Breakup by Therapeutic Area:

• Oncology
• Neurology
• Immunology
• Toxicology
• Others
   

Toxicology dominates the rat model market statistics

The report has provided a detailed breakup and analysis of the market based on the therapeutic area. This includes oncology, neurology, immunology, toxicology, and others. According to the report, toxicology represented the largest market segmentation.

Rat models are indispensable in toxicology studies due to their physiological similarities to humans.

Breakup by End User:

• Contract Research Organizations (CROs)
• Academic and Research Institutes
• Pharmaceutical and Biotechnology Companies
   

Pharmaceutical and biotechnology companies dominate the rat model market demand

The report has provided a detailed breakup and analysis of the market based on the end user. This includes contract research organizations (CROs), academic and research institutes, and pharmaceutical and biotechnology companies. According to the report, pharmaceutical and biotechnology companies represented the largest market segmentation.

The growing need for evaluation of drug efficacy, safety, and pharmacokinetics before clinical trials is augmenting the market. For example, Envigo launched the long-evans knockout (LEKO) rat, engineered to have specific gene deletions.

Breakup by Region:

• North America
  • United States
  • Canada
• Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Others
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
• Latin America
  • Brazil
  • Mexico
  • Others
• Middle East and Africa
   

North America exhibits a clear dominance in the market

The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.

As per the rat model market overview, the widespread advancements in genetic engineering are acting as significant growth-inducing factors for the rat model market in North America. One such notable launch is Charles River Laboratories’ NCI-60 human tumor cell line panel in rats for more accurate cancer research.

Competitive Landscape:

The market research report has provided a comprehensive analysis of the competitive landscape. Detailed profiles of all major rat model market companies have also been provided. Some of the key players in the market include:

• Biomere
• Charles River Laboratories International Inc.
• Cyagen Biosciences Inc.
• Envigo (Inotiv Inc.)
• genOway S.A.
• Janvier Labs
• Taconic Biosciences Inc.
• TransViragen Inc.
   

(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)

Rat Model Market Recent Developments:

• June 2024: Google’s AI division DeepMind introduced a computerized rat model that is able to move around like a real rodent through an artificial brain.
• April 2024: NZ Anti-Vivisection Society launched a rat rehoming program with the University of Auckland to rehome rats bred or used for science. 
• March 2024: The International Brain pH Project Consortium unveiled findings in a large-scale animal model study that indicate altered brain pH and lactate levels as a transdiagnostic endophenotype in neuropsychiatric disorders with cognitive impairment.

Rat Model Market Report Scope:

Key Questions Answered in This Report:

• How has the global rat model market performed so far, and how will it perform in the coming years?
• What are the drivers, restraints, and opportunities in the global rat model market?
• What is the impact of each driver, restraint, and opportunity on the global rat model market growth?
• What are the key regional markets?
• Which countries represent the most attractive rat model market?
• What is the breakup of the market based on the model type?
• Which is the most attractive model type in the rat model market?
• What is the breakup of the market based on technology?
• Which is the most attractive technology in the rat model market?
• What is the breakup of the market based on the service?
• Which is the most attractive service in the rat model market?
• What is the breakup of the market based on the therapeutic area?
• Which is the most attractive therapeutic area in the rat model market?
• What is the breakup of the market based on the end user?
• Which is the most attractive end user in the rat model market?
• What is the competitive structure of the global rat model market?
• Who are the key players/companies in the global rat model market?

Key Benefits for Stakeholders:

• IMARC's industry report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the rat model market from 2019-2033.
• The research report provides the latest information on the market drivers, challenges, and opportunities in the global rat model market.
• The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
• Porter's five forces analysis assists stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the rat model industry and its attractiveness.
• The competitive landscape allows stakeholders to understand their competitive environment and provides insight into the current positions of key players in the market.