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Top Manufacturers in the Cell-Based Assay Industry

The global cell-based assay market reached nearly US$ 17.7 Billion in 2020. The market is further projected to exhibit strong growth during 2021-2026. As per the analysis by IMARC Group, the top cell-based assay companies are adopting the latest techniques for evaluating a vast array of functional, biological and biochemical effects, including cell proliferation, apoptosis and necrosis, cell signaling, gene activation and antibody-dependent cellular cytotoxicity (ADCC). They are also investing in research and development (R&D) activities to develop better and safer drugs.

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Top Cell-Based Assay Industry Manufacturers: 

Becton Dickinson and Company

Establishment: 1906
Headquarter: New Jersey, United States
Becton, Dickinson and Company (also referred to as “BD”) is a global medical technology company engaged in developing, manufacturing and selling a broad range of medical supplies, devices, laboratory equipment and diagnostic products used by healthcare institutions, physicians, life science researchers, clinical laboratories and the pharmaceutical industry, and the general public. BD’s operations consist of three worldwide business segments: BD Medical, BD Life Sciences, and BD Interventional. Moreover, the company provides custom solutions that are focused on improving medication management and patient safety; supporting infection prevention practices; equipping surgical and interventional procedures; improving drug delivery; aiding anesthesiology care; enhancing the diagnosis of infectious diseases and cancers; advancing cellular research and applications; and supporting the management of diabetes.

Danaher Corporation

Establishment: 1969
Headquarter: Washington, District of Columbia, United States
Danaher Corporation, originally DMG, Inc., was organized as a Massachusetts real estate investment trust. In 1978, it was reorganized as a Florida corporation under the name Diversified Mortgage Investors, Inc. In 1980, the company became a subsidiary of a newly created holding company named DMG, Inc. and adopted the name Danaher in 1984. It was incorporated as a Delaware corporation in 1986. Danaher Corporation designs, manufactures, and markets professional, medical, industrial, and commercial products and services. Its research and development, manufacturing, sales, distribution, service, and administrative facilities are located in more than 60 countries. However, the company operates through three segments: Life Sciences, Diagnostics and Environmental and applied solutions. The life sciences segment offers a range of research tools that scientists use to study the basic building blocks of life, including genes, proteins, metabolites, and cells, to understand the causes of disease, identify new therapies, and test new drugs and vaccines. Its Diagnostics segment offers analytical instruments, reagents, consumables, software and services; and Environmental & Applied Solutions segment consists of various lines of business, including water quality and product identification.

Thermo Fisher Scientific Inc.

Establishment: 1956
Headquarter: Massachusetts, United States
Thermo Fisher is a Delaware corporation that completed its initial public offering in 1967 and was listed on the New York Stock Exchange in 1980. The company serves more than 400,000 customers working in pharmaceutical and biotech companies, hospitals, clinical diagnostic labs, universities, research institutions, and government agencies. In April 2019, Thermo Fisher acquired Brammer Bio, expanding its contract manufacturing capabilities to include a full range of viral vector development and manufacturing services. The company operates through four segments: Life Sciences Solutions, Analytical Instruments, Specialty Diagnostics, and Laboratory Products and Services. It offers its products and services through various brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, and Unity Lab Services. Life Sciences Solutions segment provides a portfolio of reagents, instruments, and consumables used in biological and medical research, discovery and production of new drugs and vaccines. The analytical instruments segment provides a broad offering of instruments, consumables, software, and services for a range of applications in the laboratory. The Specialty Diagnostics segment offers various diagnostic test kits, reagents, culture media, instruments, and associated products. Its Laboratory Products and Services segment provide products and solutions needed for the laboratory.

General Electric Company

Establishment: 1892
Headquarter: Massachusetts, United States
General Electric (GE) was established in New York through a merger between Thomson-Houston and Edison General Electric. General Electric Company is a high-tech industrial company that operates worldwide through its four reporting industrial segments, Power, Renewable Energy, Aviation and Healthcare, and its financial services segment, Capital. The Power segment offers technologies, solutions, and services related to energy production. The Renewable Energy segment provides wind turbine platforms, hardware, software, offshore wind turbines, solutions, products, and services to the hydropower industry. The Aviation segment provides jet engines and turboprops for commercial and military airframes, maintenance, component repair, overhaul services, replacement parts, additive machines and materials, and engineering services. The Healthcare segment provides healthcare technologies in medical imaging, digital solutions, patient monitoring and diagnostics. The Capital segment leases and finances aircraft, aircraft engines, and helicopters to provide financial and underwriting solutions and manage its run-off insurance operations. They serve customers in over 170 countries. In 2019, GE spun off and merged its Transportation segment with US rail equipment producer Wabtec in exchange for $2.9 billion in cash and a 24.3% stake in the company. The division supplies locomotives, mining equipment, marine diesel and stationary power diesel engines for land and offshore drilling. It also provides maintenance, repair, and upgrade services and efficient software.

Merck KGaA (Merck Group)

Establishment: 1668
Headquarter: Darmstadt, Germany
Merck KGaA is a Germany-based science and technology company; it is a private subsidiary of Merck Group. The company operates in three business segments: Healthcare, Life Sciences, and Performance Materials. The Healthcare business, which operates in the United States and Canada as EMD Serono, focuses on therapeutic areas, such as allergies, fertility, oncology and neurodegenerative diseases, developing drugs, diagnostic substances, and medical devices. The Life Sciences business comprises Millipore Sigma activities, which provides solutions that facilitate biotechnology and pharmaceutical research. The product range includes laboratory water systems, gene-editing tools, cell lines, and end-to-end drug manufacturing systems. The Performance Materials business provides specialty chemicals for various applications, including liquid crystals for electronic displays, materials for integrated circuits, effect pigments for coatings and color cosmetics, as well as functional materials for energy solutions.

PerkinElmer, Inc.

Establishment: 1937
Headquarter: Darmstadt, Germany
PerkinElmer was founded by Richard Perkin and Charles Elmer to design optical products. The company moved into the analytical instruments business in the 1940s. In 2019, PerkinElmer acquired Cisbio Bioassays, a custom assay service provider, for $219.9 million in cash. It is a provider of products, services, and Cisbio Bioassays that develops and manufactures kits and reagents for life sciences and diagnostics applications. It also provides a broad range of immunoassays for in vitro diagnostics, mainly tailored for cancerous pathologies, metabolic and auto-immune diseases. PerkinElmer operates through two segments: Discovery & Analytical Solutions and Diagnostics. Its discovery & analytical solutions segment serves the life sciences and applied markets. Its diagnostics segment offers instruments, reagents, assay platforms, and software to hospitals, medical labs, clinicians, and medical research professionals. It also provides early detection for genetic disorders from pregnancy to early childhood and infectious disease testing for the diagnostics market.

Charles River Laboratories

Establishment: 1947
Headquarter: Darmstadt, Germany
Charles River Laboratories offers clinical tests and drug development services. It also provides test and development services for vaccines, biosimilars, and medicine to treat the cardiovascular, skeletal, endocrine, central nervous system, cancer, and other sorts of ailments. Charles River Laboratories has more than 90 facilities and provides its services in more than 20 countries globally. The company includes three business segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Support (Manufacturing). The RMS segment includes Research Models and Research Model Services. The DSA segment provides Discovery Services and Safety Assessment. Its manufacturing segment includes Microbial Solutions, Avian, Biologics, and Contract Manufacturing. The company also offers a suite of products and services to support its clients' manufacturing activities. In 1984, the company was acquired by Bausch & Lomb, but in 1997, Jim Foster buys the company back from Bausch & Lomb.

Lonza Group AG

Establishment: 1897
Headquarter: Basel-Stadt, Switzerland

Lonza Group AG is engaged in fine producing organic chemicals, biocides, active ingredients, and biotechnology products. Lonza Group also produces active chemical and pharmaceutical ingredients and assists in developing and manufacturing a range of products. The company provides custom chemical manufacturing and fermentation processing and manufactures its products for the life sciences, pharmaceuticals, food processing, and agricultural products industries. Its Bioscience, Life Science Ingredients, and Microbial Control segments make and sell biological research materials, nutritional ingredients, and products for hygiene and water treatment. In 2011, the company acquired Arch Chemicals.

Cell Signaling Technology

Establishment: 1999
Headquarter: Massachusetts, United States
Cell Signaling Technology (CST) is a private, family-owned company, engaged in diagnostic research services. The Company offers nature biotechnology, cell, journal of immunology, and biological chemistry research. The company’s product portfolio includes Antibodies and Antibody Conjugates.

Promega Corporation

Establishment: 1978
Headquarter: Wisconsin, United States
Promega corporation provides tools for researchers to delve into the life sciences and offers biological and pharmacy products. The company’s product portfolio includes Cellular analysis, Genetic identity, Genomics, Proteomics, etc. It also provides reagents, instrumentations, and enzyme systems. Its offerings fall into various categories, including DNA and RNA purification, genotype analysis, protein expression and analysis, and DNA sequencing. Promega corporation customers include academic, pharmaceutical, clinical labs, government agencies, and energy & chemical companies, and it has branches in 15 countries around the world.

Cell Biolabs, Inc.

Establishment: 2004
Headquarter: Basel-Stadt, Switzerland
Cell Biolabs, Inc.'s line of business includes providing professional analytic or diagnostic services for the medical profession. Its products include DNA and RNA purification, genotype analysis, protein expression and analysis, and DNA sequencing. The company's core area includes Cell-Based Assays, Viral Expression, and Purification Kits and Reagents, Oxidative Stress Assays, Metabolism Research Assays and Reagents, Cell Signaling and Protein Biology.

Discoverx Corporation (Eurofins Scientific)

Establishment: 1987
Headquarter: Luxembourg
DiscoveRx Corporation develops, manufactures, and markets reagents and cell-based assay kits. The company provides cells, assay ready kits, detection reagents, cell culture kits and reagents, ligand, and inhibitors, as well as provides services including GPCR, contract, nuclear receptor, pathway, and kinase screening and profiling. The company’s products are applied in drug discovery and development, cell banks for bioassays and reagents detections.

Bio-Rad Laboratories, Inc.

Establishment: 1952
Headquarter: California, United States
Discover Bio-Rad Laboratories, Inc., incorporated on March 10, 1975, operates a chain of laboratories. The company manufactures and distributes life science research products, clinical diagnostics, and analytical instruments. The Company operates through two segments: Life Science and Clinical Diagnostics. The life science segment includes reagents, apparatus, and laboratory instruments. Its products are used in research techniques, biopharmaceutical production processes, and food testing regimes. Its clinical diagnostics segment includes designing, manufacturing, selling, and supporting test systems, informatics systems, test kits, and specialized quality controls that serve clinical laboratories. In mid-2019, Bio-Rad acquired Texas-based Exact Diagnostics, a molecular diagnostic quality control manufacturer.

Corning, Inc.

Establishment: 1851
Headquarter: New York, United States
Corning, Inc. established as a glass business company, changed its name from Corning Glass Works to Corning Incorporated on April 28, 1989. Corning Incorporated is engaged in manufacturing specialty glass and ceramics. The Company's segments include Display Technologies, Optical Communications, Environmental Technologies, Specialty Materials, Life Sciences, and all others. The display technologies segment manufactures glass substrates for flat-panel liquid crystal displays and other high-performance display panels. The optical communications segment manufactures carrier network and enterprise network components for the telecommunications industry. The specialty materials segment manufactures products that provide more than 150 material formulations for glass, glass ceramics, and fluoride crystals. The environmental technologies segment manufactures ceramic substrates and filters for automotive and diesel applications. The life sciences segment manufactures glass and plastic labware, equipment, media, serum, and reagents, enabling workflow solutions for drug discovery and bioproduction.

Hoffmann-La Roche Ltd. (Roche Holdings AG)

Establishment: 1896
Headquarter: Basel, Switzerland

F. Hoffmann-La Roche & Co. was founded when the industrial revolution was changing the face of Europe. On October 1, 1896, at the age of 28, Fritz Hoffmann-La Roche launched his company as the successor company to Hoffmann, Traub & Co in Basel, Switzerland. F. Hoffmann-La Roche Ltd (Roche) is a biotechnology company that develops drugs and diagnostics to treat major diseases. It develops medicines for various disease areas such as oncology, immunology, infectious diseases, ophthalmology, and neuroscience. The company's operating businesses are divided into two divisions: Pharmaceuticals and Diagnostics. The Pharmaceuticals Division consists of two business segments: Roche Pharmaceuticals and Chugai. Its Diagnostics Division consists of four business areas: Diabetes Care, Molecular Diagnostics, Professional Diagnostics, and Tissue Diagnostics. Its pharmaceutical products include Anaprox, Avastin, Bactrim, Bondronat, CellCept, Cotellic, Dilatrend, Dormicum, Invirase, Kadcyla, Kytril (Kevatril), genome sequencing and nucleic acid purification, etc.
 

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