Musculoskeletal Pain Market Size, Epidemiology, In-Market Drugs Sales, Pipeline Therapies, and Regional Outlook 2025-2035

Musculoskeletal Pain Market Size, Epidemiology, In-Market Drugs Sales, Pipeline Therapies, and Regional Outlook 2025-2035

Report Format: PDF+Excel | Report ID: SR112025A8132

Market Overview:

The musculoskeletal pain market reached a value of USD 4,087.8 Million across the top 7 markets (US, EU4, UK, and Japan) in 2024. Looking forward, IMARC Group expects the top 7 major markets to reach USD 5,757.9 Million by 2035, exhibiting a growth rate (CAGR) of 3.19% during 2025-2035.

Report Attribute
Key Statistics
Base Year
2024
Forecast Years 2025-2035
Historical Years
2019-2024
Market Size in 2024
USD 4,087.8 Million
Market Forecast in 2035
USD 5,757.9 Million
Market Growth Rate (2025-2035)
3.19%


The musculoskeletal pain market has been comprehensively analyzed in IMARC's new report titled "Musculoskeletal Pain Market Size, Epidemiology, In-Market Drugs Sales, Pipeline Therapies, and Regional Outlook 2025-2035". Musculoskeletal pain refers to discomfort or pain that affects the muscles, bones, ligaments, tendons, or other structures that support the body's movement. The pain associated with this ailment can be acute, lasting for a shorter amount of time, or chronic, extending for several weeks, months, or even years. The symptoms can vary in intensity based on the specific area of the body affected. Some common indications include a dull, aching sensation to sharp, intense pain, stiffness, swelling, muscle weakness, tenderness, limited range of motion, etc. Individuals suffering from this disease may also experience a sense of overall tiredness due to poor sleep quality. The diagnosis of musculoskeletal pain is based on a review of the patient's medical history, clinical features, and physical exam. The healthcare professional may also perform several diagnostic procedures, such as X-rays, ultrasounds, magnetic resonance imaging, etc., to obtain detailed images of the soft tissues that may indicate the causes of the underlying symptoms. In some cases, electromyography is recommended to measure the electrical activity of nerves and muscles in patients.

Musculoskeletal Pain Market

The rising cases of acute injuries, such as sprains and fractures, which can lead to localized pain in the affected muscles, ligaments, tendons, bones, etc., are primarily driving the musculoskeletal pain market. In addition to this, the increasing incidences of several associated risk factors, including obesity, genetic predisposition, sedentary lifestyle, excessive physical activity, muscular imbalance, poor posture, etc., are further augmenting the market growth. Moreover, the emerging popularity of effective medications, such as nonsteroidal anti-inflammatory drugs, muscle relaxants, pain relievers, etc., to relieve disease symptoms is also creating a positive outlook for the market. Apart from this, the widespread adoption of massage therapy, which helps to relax muscles, improve blood circulation, reduce muscle tension, and alleviate pain, is further bolstering the market growth. Additionally, the escalating utilization of cognitive-behavioral therapy to treat the condition, since it can identify and modify negative thought patterns and behaviors, is acting as another significant growth-inducing factor. Besides this, the rising demand for mindfulness-based stress reduction techniques that can promote relaxation and enhance overall well-being among patients is expected to drive the musculoskeletal pain market in the coming years. 

IMARC Group's new report provides an exhaustive analysis of the musculoskeletal pain market in the United States, EU4 (Germany, Spain, Italy, and France), the United Kingdom, and Japan. This includes treatment practices, in-market and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report, the United States has the largest patient pool for musculoskeletal pain and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario, and unmet medical needs etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the musculoskeletal pain market in any manner.

Time Period of the Study

  • Base Year: 2024
  • Historical Period: 2019-2024
  • Market Forecast: 2025-2035

Countries Covered

  • United States
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Japan

Analysis Covered Across Each Country

  • Historical, current, and future epidemiology scenario
  • Historical, current, and future performance of the musculoskeletal pain market
  • Historical, current, and future performance of various therapeutic categories in the market
  • Sales of various drugs across the musculoskeletal pain market
  • Reimbursement scenario in the market
  • In-market and pipeline drugs

Competitive Landscape:

This report also provides a detailed analysis of the current musculoskeletal pain marketed drugs and late-stage pipeline drugs.

In-Market Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance
Drugs Company Name
Amrix (cyclobenzaprine hydrochloride) Teva Pharmaceuticals
Cymbalta (Duloxetine) Eli Lilly and Company
Resiniferatoxin Grünenthal
Pentosan polysulfate Paradigm Biopharma
LNK-01001 Lynk Pharmaceuticals
Rexlemestrocel-L Mesoblast
X0002 Techfields Pharma


*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:

Market Insights

  • How has the musculoskeletal pain market performed so far and how will it perform in the coming years?
  • What are the markets shares of various therapeutic segments in 2024 and how are they expected to perform till 2035?
  • What was the country-wise size of the musculoskeletal pain across the seven major markets in 2024 and what will it look like in 2035?
  • What is the growth rate of the musculoskeletal pain across the seven major markets and what will be the expected growth over the next ten years?
  • What are the key unmet needs in the market?

Epidemiology Insights

  • What is the number of prevalent cases (2019-2035) of musculoskeletal pain across the seven major markets?
  • What is the number of prevalent cases (2019-2035) of musculoskeletal pain by age across the seven major markets?
  • What is the number of prevalent cases (2019-2035) of musculoskeletal pain by gender across the seven major markets?
  • What is the number of prevalent cases (2019-2035) of musculoskeletal pain by type across the seven major markets?
  • How many patients are diagnosed (2019-2035) with musculoskeletal pain across the seven major markets?
  • What is the size of the musculoskeletal pain patient pool (2019-2024) across the seven major markets?
  • What would be the forecasted patient pool (2025-2035) across the seven major markets?
  • What are the key factors driving the epidemiological trend musculoskeletal pain of?
  • What will be the growth rate of patients across the seven major markets?

Musculoskeletal Pain: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current marketed drugs and what are their market performance?
  • What are the key pipeline drugs and how are they expected to perform in the coming years?
  • How safe are the current marketed drugs and what are their efficacies?
  • How safe are the late-stage pipeline drugs and what are their efficacies?
  • What are the current treatment guidelines for musculoskeletal pain drugs across the seven major markets?
  • Who are the key companies in the market and what are their market shares?
  • What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the musculoskeletal pain market?
  • What are the key regulatory events related to the musculoskeletal pain market?
  • What is the structure of clinical trial landscape by status related to the musculoskeletal pain market?
  • What is the structure of clinical trial landscape by phase related to the musculoskeletal pain market?
  • What is the structure of clinical trial landscape by route of administration related to the musculoskeletal pain market?

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Musculoskeletal Pain Market Size, Epidemiology, In-Market Drugs Sales, Pipeline Therapies, and Regional Outlook 2025-2035
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