Vaccine Adjuvants Market Report by Product Type (Adjuvant Emulsions, Pathogen Components, Particulate Adjuvants, Combination Adjuvants, and Others), Route of Administration (Oral, Intramuscular, Intranasal, Subcutaneous, Intradermal, and Others), Diseases (Cancer, Infectious Diseases, and Others), Application (Research, Commercial), and Region 2024-2032

Vaccine Adjuvants Market Report by Product Type (Adjuvant Emulsions, Pathogen Components, Particulate Adjuvants, Combination Adjuvants, and Others), Route of Administration (Oral, Intramuscular, Intranasal, Subcutaneous, Intradermal, and Others), Diseases (Cancer, Infectious Diseases, and Others), Application (Research, Commercial), and Region 2024-2032

Report Format: PDF+Excel | Report ID: SR112024A4385
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Vaccine Adjuvants Market Size:

The global vaccine adjuvants market size reached US$ 996.5 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 2,639.3 Million by 2032, exhibiting a growth rate (CAGR) of 11.1% during 2024-2032. Global vaccine adjuvants market is growing rapidly due to the rising incidence of infectious diseases, significant milestones in immunology and vaccine technology, the escalating awareness of rare disease, the increased interest in pandemic vaccination efforts among the unbuilt population, burgeoning government spending, and the need for effective vaccination for the elderly.

Report Attribute
Key Statistics
Base Year
2023
Forecast Years
2024-2032
Historical Years
2018-2023
Market Size in 2023 US$ 996.5 Million
Market Forecast in 2032 US$ 2,639.3 Million
Market Growth Rate (2024-2032) 11.1%


Vaccine Adjuvants Market Analysis:

  • Major Market Drivers: The vaccine adjuvants market outlook is expanding based on various factors, such as growing emphasis on personalized medicine taking place globally adjusts vaccine formulations to the unique immunological needs of each individual, driving a large share of the vaccine adjuvants market expansion. Moreover, novel technologies in bioinformatics and systems biology have led to a deeper understanding of immune responses and subsequent refinement in adjuvant design, contributing considerably to the vaccine adjuvants market demand. Apart from this, with the influx of therapeutic vaccines for chronic diseases such as cancer and Alzheimer’s, a significant avenue has been opened to expand the adjuvant’s application, supplemented by the rise in antibiotic resistance that demands the development of more robust vaccines, which is further propelling the vaccine adjuvants market growth. There have also been numerous environmental changes and rising pathogen threats that contribute to dynamic changes, promoting the need for constant adjuvant innovation.
  • Key Market Trends: The key vaccine adjuvants market trends include to shift to synthetic and molecularly defined adjuvants as a means of enhancing the safety and efficacy profile of adjuvants. Another factor contributing to the vaccine adjuvants market share is the move towards adjuvant systems that can stimulate both humoral and cellular immunity as an approach that recognizes the multiple levels of complexity in such conditions and treatments and translates into an advanced vaccine adjuvants market forecast. The interest in mucosal vaccines has also grown, as these vaccines offer more comprehensive protection by targeting the origin site of infection. Sustainable and economically feasible production is another trend, which is a critical component for the future of vaccine adjuvants market.
  • Geographical Trends: Currently, the global leader in vaccine adjuvants market overview is North America based on robust healthcare infrastructure and research and development (R&D) funding, making it a global leader. Moreover, high public awareness has increased the vaccine adjuvants market price supported by presence of large pharmaceuticals and innovation from leading research institutes. Hence, the most vaccine adjuvants market statistics are expressed in the improved safety profiles, efficacy improvements, and cost reductions. European and Asia-Pacific regions hold the highest potential due to rising healthcare spending and awareness of vaccine-preventable diseases.
  • Competitive Landscape:  Some of the major market players in the vaccine adjuvants industry include Adjuvatis, Agenus Inc., Croda International Plc, CSL Limited, Dynavax Technologies, InvivoGen, Novavax Inc., OZ Biosciences, Phibro Animal Health Corporation, SEPPIC, SPI Pharma, etc.
  • Challenges and Opportunities: The most significant challenge in the vaccine adjuvants market is the regulatory and safety issues associated with extensive clinical trial and testing to prove the adjuvants’ efficacy and possible health risks. However, promising the future, it’s an opportunity in different aspects. The COVID-19 pandemic has surged the investments in the vaccine adjuvants market. As a result, the vaccine adjuvants market analysis continues to grow, exploring novel adjuvants to revolutionize vaccine design densifies the global health safety.


Vaccine Adjuvants Market Trends:

Advancements in Vaccine and Immunology Technology

Immunology has made significant strides in vaccine adjuvant development, with new adjuvants being both more effective and safer than previously thought. Technological progress allows to design adjuvants that can selectively increase immune response to an antigen, which significantly increased vaccines’ capability to fight a wide range of pathogens around the world. Recently, in February 2024, AbbVie , and Tentarix Biotherapeutics revealed the multi-year strategic partnership to develop biologic candidates in oncology and immunology. The agreement is valued more than USD 64 million. The drug candidates will be developed to combine AbbVie’s capabilities in oncology and immunology with Tentarix’s proprietary Tentacles platform to discover and develop conditionally active, multi-specific biologics against one target in each branch of medicine. This will activate immune cells that can modulate disease pathways while reducing the safety concern,  typically associated with non-specific treatment.

Rising Awareness and Understanding of Rare Diseases

The growing recognition for rare diseases has accelerated distinctive challenges in the vaccine development. This new awareness has piqued the interest in vaccine adjuvants that can be customized to the specific needs of various stakeholders. As regards to the European Union, they defined RDs as affecting less than 50 per 100,000 people in the European population. However, the American Orphan Drug Act, outpatient, defined RDs as affecting less than 200,000 people in the United States. Other definitions included one as low as 5 per 100,000 people in Congo, while the highest was 76 per 100,000 people in India . On average, RDs affects 40 in every 100,000 people in the world. Recently, the prevalence of Rare Diseases prevalence, based on 3,585 RDs, was between 3.5 to 5.9 percent of the world population, equaling 263 to 446 million individuals.

Global Push for Vaccinations Against Pandemic Threats

The fight against the threat of pandemics, exemplified by COVID-19, sparked an unprecedented global vaccination crusade, propelling the vaccine adjuvants market into the spotlight of priority public health concerns. This frantic crusade quickened the pace of research, development, and distribution of new and novel adjuvants intended to increase the number of vaccines capable of controlling deadly, fast-spreading infections. “There were 15,141 new weekly hospital admissions for COVID-19, according to the ABC news. That’s about the same as in early April 2024, according to information from the Centers for Disease Control and Prevention (CDC). But it’s not as high as the peak of 150,650 hospitalizations per week for the week of Jan. 22, 2022, during the omicron wave”. In total, more than 6 million Americans have been hospitalized over the course of the pandemic, the CDC reports.

Vaccine Adjuvants Market Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the market, along with forecasts at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on product type, route of administration, diseases, and application.

Breakup by Product Type:

Vaccine Adjuvants Market

  • Adjuvant Emulsions
  • Pathogen Components
  • Particulate Adjuvants
  • Combination Adjuvants
  • Others
     

Adjuvant Emulsions accounts for the majority of the market share

The report has provided a detailed breakup and analysis of the market based on the product type. This includes adjuvant emulsions, pathogen components, particulate adjuvants, combination adjuvants, and others. According to the report, adjuvant emulsions represented the largest segment.

The adjuvant emulsions segment is driven by the increasing demand for vaccines with enhanced efficacy and longer-lasting immunity. This interest stems from the ability of emulsion-based adjuvants to provoke a strong and broad immune response, making them ideal for use in vaccines against complex diseases such as influenza and COVID-19. The versatility of emulsion adjuvants, compatible with a wide range of antigens, further boosts their appeal. Additionally, advancements in nanotechnology have improved the delivery mechanisms of these adjuvants, increased their effectiveness while maintaining safety profiles. The ongoing research and development efforts aimed at optimizing emulsion formulations are crucial in meeting the growing vaccine adjuvants market demand, underscoring their pivotal role in future vaccine development strategies.

Breakup by Route of Administration:

  • Oral
  • Intramuscular
  • Intranasal
  • Subcutaneous
  • Intradermal
  • Others
     

 Intramuscular represents the leading market segment 

The report has provided a detailed breakup and analysis of the market based on the route of administration. This includes oral, intramuscular, intranasal, subcutaneous, intradermal, and others. According to the report, intramuscular represented the largest segment.

 The intramuscular segment is driven by the increasing demand for vaccines that require deep tissue penetration for optimal efficacy, such as vaccines against influenza, tetanus, and COVID-19. This method is preferred for its ability to deliver larger volumes of a vaccine directly into the muscle, where there is a rich blood supply, facilitating a stronger and quicker immune response. Additionally, the intramuscular route is favored for its relative ease of administration, minimal discomfort, and lower risk of adverse reactions compared to other methods, making it a widely accepted practice in vaccination programs globally. The consistency in vaccine absorption rates and the extensive historical data supporting its effectiveness further bolster its adoption, underlining the segment's growth.

Breakup by Diseases:

  • Cancer
  • Infectious Diseases
  • Others
     

 Infectious diseases accounts for the majority of the market share

The report has provided a detailed breakup and analysis of the market based on the disease. This includes cancer, infectious diseases, and others. According to the report, infectious diseases represented the largest segment.

 The infectious diseases segment is driven by the increasing prevalence of global pandemics and emerging infectious threats, which highlight the critical need for effective vaccines. Factors such as international travel, urbanization, and climate change contribute to the spread of infectious diseases, necessitating rapid development and deployment of vaccines with potent adjuvants. The segment's growth is further fueled by governmental and international initiatives to combat infectious diseases, alongside significant investments in research and development. Moreover, public awareness and healthcare infrastructure improvements play essential roles in supporting vaccination programs, thereby enhancing the demand for innovative vaccine adjuvants tailored to combat these diseases effectively.

Breakup by Application:

  • Research
  • Commercial
     

Research represents the leading market segment 

The report has provided a detailed breakup and analysis of the market based on the application. This includes research and commercial. According to the report, research represented the largest segment.

The research segment in the vaccine adjuvants market is driven by the increasing demand for more efficacious vaccines against a broader range of pathogens, including emerging and re-emerging infectious diseases. This need is coupled with a growing understanding of the immune system's complexities, prompting scientists to explore novel adjuvant formulations that can elicit stronger and more durable immune responses. Additionally, the push for personalized medicine and vaccines tailored to individual genetic makeups fuels the exploration of innovative adjuvants. Advances in biotechnology and nanotechnology further drive this segment, enabling the development of next-generation adjuvants that can be precisely engineered to enhance vaccine effectiveness while minimizing side effects.

Breakup by Region:

Vaccine Adjuvants Market

  • North America
    • United States
    • Canada
  • Asia-Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Indonesia
    • Others
  • Europe
    • Germany
    • France
    • United Kingdom
    • Italy
    • Spain
    • Russia
    • Others
  • Latin America
    • Brazil
    • Mexico
    • Others
  • Middle East and Africa
     

North America leads the market, accounting for the largest vaccine adjuvants market share

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for vaccine adjuvants.

The North America’s vaccine adjuvants are expected to dominate the market due to extensive investment in researching and developing (R&D) vaccines that are aimed at tackling a wide range of infectious illnesses and rising health concerns from both the public and private sectors. The region has the advantage of a rapid approval process for vaccines, which encourages drug companies to expand and boost investments into adjuvant technologies. Furthermore, North America has many of the top research centers superiority and frequent collaboration with the biotech sector. As a result, it is the field of medical technology and innovation. In addition, to improve the effectiveness of vaccines, adjuvants, are used with greater awareness of the importance of boosting the effectiveness and safety of vaccines, driving market expansion in North America.

Competitive Landscape:

  • The market research report has also provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the major market players in the vaccine adjuvants industry include Adjuvatis, Agenus Inc., Croda International Plc, CSL Limited, Dynavax Technologies, InvivoGen, Novavax Inc., OZ Biosciences, Phibro Animal Health Corporation, SEPPIC, SPI Pharma, etc.
  • Key players in the vaccine adjuvants market are actively engaging in research and development activities to introduce innovative and more effective adjuvant formulations. These efforts are aimed at enhancing the immune response elicited by vaccines, ensuring broader and more durable protection against a variety of infectious diseases and for therapeutic vaccines targeting chronic conditions such as cancer. For instance, in February 2022,  Novavax Inc. announced positive interim results from their Phase 3 clinical trial evaluating their COVID-19 vaccine candidate, NVX-CoV2373, combined with their proprietary adjuvant, Matrix-M. The results showed strong efficacy against COVID-19, demonstrating an overall efficacy of over 90%. Collaborations and partnerships are a common strategy, uniting expertise from academic institutions, research organizations, and biotechnology firms to accelerate the development of next-generation adjuvants. Furthermore, these companies are investing in advanced technologies and exploring novel adjuvant substances, including synthetic molecules and natural compounds, to improve vaccine efficacy and safety profiles. Regulatory compliance and the pursuit of fast-track approval processes are also critical, as companies navigate the complex landscape to bring their innovations to market. Through these actions, key players are significantly contributing to the dynamic growth and evolution of the global vaccine adjuvants market.


Vaccine Adjuvants Market News:

  • In September 2022: Dynavax Technologies embarked on a significant endeavor by commencing a Phase 2 clinical trial for their COVID-19 vaccine candidate, DVX-COV2373. This vaccine, formulated with the company's proprietary adjuvant CpG 1018, represents a promising avenue in the ongoing fight against the COVID-19 pandemic. What distinguishes this trial is its collaboration with the Coalition for Epidemic Preparedness Innovations (CEPI), a global partnership focused on accelerating the development of vaccines against emerging infectious diseases. The primary objective of this Phase 2 trial is to expand upon earlier findings and evaluate DVX-COV2373's safety and efficacy in a larger population. This step is crucial in ensuring that the vaccine meets stringent regulatory standards while also gauging its performance across diverse demographics.
  • In February 2024: CSL (ASX:CSL; USOTC:CSLLY) announced top-line results from the Phase 3 AEGIS-II trial evaluating the efficacy and safety of CSL112 (apolipoprotein A-I [human]) compared to placebo in reducing the risk of major adverse cardiovascular events (MACE) in patients following an acute myocardial infarction (AMI).


Vaccine Adjuvants Market Report Scope:

Report Features Details
Base Year of the Analysis 2023
Historical Period 2018-2023
Forecast Period 2024-2032
Units US$ Million
Scope of the Report Exploration of Historical Trends and Market Outlook, Industry Catalysts and Challenges, Segment-Wise Historical and Future Market Assessment:
  • Product Type
  • Route of Administration
  • Diseases
  • Application
  • Region
Product Types Covered Adjuvant Emulsions, Pathogen Components, Particulate Adjuvants, Combination Adjuvants, Others
Route of Administrations Covered Oral, Intramuscular, Intranasal, Subcutaneous, Intradermal, Others
Diseases Covered Cancer, Infectious Diseases, Others
Applications Covered Research, Commercial
Regions Covered Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered United States, Canada, Germany, France, United Kingdom, Italy, Spain, Russia, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered Adjuvatis, Agenus Inc., Croda International Plc, CSL Limited, Dynavax Technologies, InvivoGen, Novavax Inc., OZ Biosciences, Phibro Animal Health Corporation, SEPPIC, SPI Pharma, etc.

(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
Customization Scope 10% Free Customization
Report Price and Purchase Option Single User License: US$ 3899
Five User License: US$ 4899
Corporate License: US$ 5899
Post-Sale Analyst Support 10-12 Weeks
Delivery Format PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request)


Key Benefits for Stakeholders:

  • IMARC’s industry report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the vaccine adjuvants market from 2018-2032.
  • The research report provides the latest information on the market drivers, challenges, and opportunities in the global vaccine adjuvants market.
  • The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
  • Porter's five forces analysis assists stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the vaccine adjuvants industry and its attractiveness.
  • The competitive landscape allows stakeholders to understand their competitive environment and provides insight into the current positions of key players in the market.

Key Questions Answered in This Report

The global vaccine adjuvants market was valued at US$ 996.5 Million in 2023.

We expect the global vaccine adjuvants market to exhibit a CAGR of 11.1% during 2024-2032.

The rising prevalence of allergies and infectious diseases, such as coronavirus infection, Human Immunodeficiency Virus (HIV), tuberculosis, etc., along with the continuous development of vaccines that have long-lasting effects on immunization, is primarily driving the global vaccine adjuvants market.

The sudden outbreak of the COVID-19 pandemic has led to the increasing demand for effective and safe vaccine adjuvants among individuals to induce long-term protection and safety against the coronavirus infection.

Based on the product type, the global vaccine adjuvants market has been divided into adjuvant emulsions, pathogen components, particulate adjuvants, combination adjuvants, and others. Among these, adjuvant emulsions currently exhibit a clear dominance in the market.

Based on the route of administration, the global vaccine adjuvants market can be categorized into oral, intramuscular, intranasal, subcutaneous, intradermal, and others. Currently, intramuscular accounts for the majority of the global market share.

Based on the diseases, the global vaccine adjuvants market has been segregated into cancer, infectious diseases, and others, where infectious diseases currently hold the largest market share.

Based on the application, the global vaccine adjuvants market can be bifurcated into research and commercial. Currently, research exhibits a clear dominance in the market.

On a regional level, the market has been classified into North America, Asia-Pacific, Europe, Latin America, and Middle East and Africa, where North America currently dominates the global market.

Some of the major players in the global vaccine adjuvants market include Adjuvatis, Agenus Inc., Croda International Plc, CSL Limited, Dynavax Technologies, InvivoGen, Novavax Inc., OZ Biosciences, Phibro Animal Health Corporation, SEPPIC, SPI Pharma, etc.

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Vaccine Adjuvants Market Report by Product Type (Adjuvant Emulsions, Pathogen Components, Particulate Adjuvants, Combination Adjuvants, and Others), Route of Administration (Oral, Intramuscular, Intranasal, Subcutaneous, Intradermal, and Others), Diseases (Cancer, Infectious Diseases, and Others), Application (Research, Commercial), and Region 2024-2032
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